| 大三阳孕妇产婴疫苗免疫分析 |
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| 引用本文： | 康玉国,张蕾,廖晓寰,王妹芳,许群欢,朱锦慧.大三阳孕妇产婴疫苗免疫分析[J].国际检验医学杂志,2005,26(5):269-270. |
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| 作者姓名： | 康玉国 张蕾 廖晓寰 王妹芳 许群欢 朱锦慧 |
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| 作者单位： | 复旦大学附属上海市第五人民医院检验科、复旦大学医学院检验学系,上海,200240;复旦大学附属上海市第五人民医院妇产科,上海,200240 |
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| 摘 要： | 目的了解大三阳孕妇所生婴儿6年后乙肝疫苗免疫情况。方法大三阳孕妇所生婴儿出生后、1个月和6个月注射乙肝疫苗;随访6年后用ELISA法检查乙肝两对半。结果未接种乙肝疫苗的大三阳孕妇新生儿6年后乙肝表面抗原阳性率90%(9/10),乙肝表面抗体阳性率10%(1/10);接种乙肝疫苗的大三阳孕妇新生儿6年后乙肝表面抗原阳性率5%(1/20),乙肝表面抗体阳性率80%(16/20)。结论新生儿接种乙肝疫苗后大大降低了乙肝表面抗原阳性率。
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| 关 键 词： | 大三阳孕妇 新生儿 乙肝疫苗 |
| 修稿时间： | 2004年5月17日 |
Follow-up of infants vaccinated hepatitis B vaccine born by women with three signs positive |
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| Abstract: | Objective To describe the current HBV incidence and epidemiology among children born by women suffering from hepatitis B.Methods Newborns were injected hepatitis B vaccine,and one month and six months later were injected hepatitis B Vaccine repeatly.Six years later fresh serum samples of the children were analyzed by ELISA.Results The HBsAg rate among children not received hepatitis B vaccine was 90%(9/10),the HBsAb rate was 10%(1/10).And the HBsAg rate among children received hepatitis B vaccine was 5%(1/20),while the HBsAb rate was 80%(16/20).Conclusion The HBsAg rate is lower among children received hepatitis B vaccine than those not received hepatitis B vaccine . |
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| Keywords: | Hepatitis B pregnant woman Infant Hepatitis B vaccine |
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