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白细胞介素2和黄芪多糖对小鼠NK细胞活性和增殖及形态的影响
引用本文:张晓明,杨景山. 白细胞介素2和黄芪多糖对小鼠NK细胞活性和增殖及形态的影响[J]. 北京大学学报(医学版), 1991, 0(3)
作者姓名:张晓明  杨景山
作者单位:北京医科大学组织胚胎学教研室(张晓明),北京医科大学组织胚胎学教研室(杨景山)
摘    要:
本实验观察了细胞介素2(IL-2)和黄芪多糖(PA)对小鼠NK细胞活性、增殖和形态的影响。结果表明,IL-2、PA均能不同程度地增强NK细胞活性、刺激NK细胞增殖,IL-2与PA合用时其效果更佳。NK细胞胞体相应变大,核质比降低。

关 键 词:白细胞介素2  黄芪多糖  NK细胞  细胞活性  细胞增殖

EFFECTS OF IL-2 AND POLYSACCHRIDE OF ASTRAGALUS ON MURINE NK ACTIVITY PROLIFERATION AND MORPHOLOGY
Zhang Xiaoming,Yang Jingshan. EFFECTS OF IL-2 AND POLYSACCHRIDE OF ASTRAGALUS ON MURINE NK ACTIVITY PROLIFERATION AND MORPHOLOGY[J]. Journal of Peking University. Health sciences, 1991, 0(3)
Authors:Zhang Xiaoming  Yang Jingshan
Affiliation:Zhang Xiaoming;Yang Jingshan Department of Histology and Embryology
Abstract:
In present study, interleukin-2 (IL-2) and polysacchride of astragalus (PA) were used to stimu-late murine natural killer(NK) cells. We found that both IL-2 and PA could enhance NK cytotoxicityand NK cell proliferation, the former being the stronger stimulater. IL-2 in collaboration with PA wasthe strongest stimulater. In addition, the morphology of NK cells were changed significantly afterbeing pretreated with IL-2 and PA.
Keywords:Interleukin-2  Polysacchride of astragalus  Natural Killer Cell  Cytotoxicity  Cell Proliferation
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