Familial Occurrence of Gestational Hypertensive Disorders in a Brazilian Population |
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| Authors: | F. M. Araujo G. Duarte J. Nomelini R. B. Lôbo E. S. Ramos |
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| Affiliation: | 1. Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeir?o Preto, University of S?o Paulo, Ribeir?o Preto, SP, Brazilfrancielle@genbov.fmrp.usp.br;3. Department of Obstetrics and Gynecology, University Hospital of Medicine School of Ribeir?o Preto, University of S?o Paulo, Ribeir?o Preto, SP, Brazil;4. Department of Genetics, University Hospital of Medicine School of Ribeir?o Preto, University of S?o Paulo, Ribeir?o Preto, SP, Brazil;5. Department of Genetics, University Hospital of Medicine School of Ribeir?o Preto, University of S?o Paulo, Ribeir?o Preto, SP, Brazil |
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| Abstract: | ![]()
Objective: To verify the occurrence of preeclampsia/eclampsia (PE/E) or gestational hypertension (GH) in first-degree relatives of Brazilian pregnant women. Methods: A total of 485 women were enrolled in the study, and 226 were selected (75 with PE/E, 49 with GH, and 102 women with normal pregnancies). Statistical analysis was performed using Fisher's exact test. Results: The frequency of families with mothers and/or sisters with PE/E was higher among the PE/E group compared to the GH and the control groups, and was statistically significant (p < 0.05). Conclusion: Women with PE/E have more female first-degree relatives with PE/E as observed in a Brazilian population. |
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| Keywords: | Preeclampsia Eclampsia Gestational hypertension Familial |
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