耳后药物注射治疗突发性聋32例

目的：观察耳后注射糖皮质激素治疗突发性聋的疗效。方法65例突聋患者分为耳后注射组（32例）和鼓室给药组（33例），除常规治疗外，两组分别经耳后注射和鼓膜穿刺给予地塞米松0．5 mg，1次／3 d，疗程14 d。结果耳后注射组和鼓室给药组听力改善分别为（13．2±8．6）dB 和（14．6±11．1）dB，两组治疗前后比较差异均有统计学意义（P ＜0．05），组间比较差异无统计学意义（P ＞0．05），不良反应试验组低于对照组（P ＜0．05）。结论突聋患者耳后局部注射糖皮质激素效果明显、操作简单、不良反应低，可作为鼓室给药有禁忌时的备选疗法。

Clinical trial of postaurical drug injection to treat sudden hearing loss

Objective To evaluate the postaurical injection of corticosteroids to treat sudden hearing loss.Methods 65 patients with sudden hearing loss were divided into postaurical injection group （n =32）and intratympanic administration group （n =33）.In addition to conventional medication,two groups were injected dexamethasone 0.5 mg through post-aurical or intratympanic approaches on every three days in a 14-day course.Results The hearing improvement in post-aurical injection group and intratympanic administration group were 13.2 ±8.6 dB and 14.6 ±11.1 dB.Compared to the pre-treatment,the differences were significant in both groups （P 〈0.05）,however,no significant difference were noted between the groups （P 〉0.05）.Adverse reactions occurred less in experimental group than the control （P 〈0.05）.Conclusion Postaurical injection is effective,simple and safe to treat sudden hearing loss,which can serve as an alternative for intratympanic administration.