Ertapenem versus piperacillin/tazobactam for the treatment of complicated infections: a meta-analysis of randomized controlled trials |
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| Authors: | Mao Mao An Zui Zou Hui Shen Jun Dong Zhang Meng Li Chen Ping Liu Rui Wang Yuan Ying Jiang |
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| Affiliation: | (1) Department of Clinical Pharmacology, Chinese People's Liberation Army General Hospital, 28 Fuxing Road, Beijing, 100853, PR China;(2) Department of Anesthesiology, Changzheng Hospital, Second Military Medical University, Shanghai, 200433, PR China;(3) Chinese Acad Med Sci, Peking Union Med Coll, Fuwai Hosp & Cardiovasc Inst, 167 Beilishi Road, Beijing, 100037, PR China;(4) Department of Pharmacology, School of Pharmacy, Second Military Medical University, 325 Guo He Road, Shanghai, 200433, PR China |
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| Abstract: | Background Ertapenem, a new carbapenem with a favorable pharmacokinetic profile, has been approved for the treatment of complicated intra-abdominal Infections (cIAIs), acute pelvic infections (APIs) and complicated skin and skin-structure infections (cSSSIs). The aim of this study is to compare the efficacy and safety of ertapenem with piperacillin/tazobactam, which has been reported to possess good efficacy for the treatment of these complicated infections. |
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