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sIL-2R、IL-6在重症肌无力胸腺瘤中的表达及意义
引用本文:迟海涛,金蕊,丛博,白鹰. sIL-2R、IL-6在重症肌无力胸腺瘤中的表达及意义[J]. 中国医药指南, 2013, 0(7): 39-40
作者姓名:迟海涛  金蕊  丛博  白鹰
作者单位:迟海涛 (大连大学附属新华医院神经内科,辽宁大连116021); 金蕊 (大连大学附属新华医院神经内科,辽宁大连116021);丛博 (大连大学附属新华医院神经内科,辽宁大连116021); 白鹰 (大连大学附属新华医院神经内科,辽宁大连116021);
摘    要:
目的探讨可溶性白细胞介素2受体(sIL-2R)、白细胞介素6(IL-6)在胸腺瘤合并MG发病机制中的作用。方法搜集胸腺切除手术的27例胸腺瘤患者的相关资料,对切除的胸腺瘤组织用免疫组化的方法,确定SIL-2R、IL-6在胸腺瘤组织中的表达情况。结果 SIL-2R细胞因子、IL-6在胸腺瘤合并MG的胸腺瘤组织呈高表达。结论可溶性白细胞介素2受体(SIL-2R)、IL-6在胸腺瘤合并MG的表达呈正相关。

关 键 词:重症肌无力  可溶性白细胞介素2受体(SIL-2R)  白细胞介素6(IL-6)  胸腺瘤

The Roles of sIL-2R, IL-6 in Pathogenesis of Thymoma with Myasthenia Gravis
CHI Hai-tao,JIN Rui,CONG Bo,BAI Ying. The Roles of sIL-2R, IL-6 in Pathogenesis of Thymoma with Myasthenia Gravis[J]. Guide of China Medicine, 2013, 0(7): 39-40
Authors:CHI Hai-tao  JIN Rui  CONG Bo  BAI Ying
Affiliation:(Department of Neurology, Xinhua Hospital Affiliated to Dalian University, Dalian 116021, China)
Abstract:
Objective To explore the roles of slL-2R, IL-6 in the pathogenesis of thymona with myasthenia gravis. Method A analysis of 27 cases of thymona for whom thymectomy were performed was made. The immunohistochemical staining with slL-2R, IL-6 was performed on the parrafined sections of the 27 thymona specimen. Results In the 27 thymectomy patients, slL-2R. Conclusion slL-2R, IL-6 are important in pathogenesis for thymoma with MG and may also initiate the MG's autoimmune reactions.
Keywords:Myasthenia gravis(MG)  sIL-2R  IL-6  Thymoma
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