蔬菜水果食用频率与慢性阻塞性肺疾病的相关性

目的 探讨中国城乡居民蔬菜和水果食用频率与慢性阻塞性肺疾病(COPD)的关系.方法 2007年在全国疾病监测系统的161个监测点中,采用多阶段按比例分层随机抽样的方法,抽取了48 974名15～69岁居民作为调查对象,采用标准化问卷调查收集相关信息,比较不同蔬菜食用频率(<4、4～5、6～7 d/周)和水果食用频率(<2、2～4、5～7 d/周)的自报COPD患病风险.结果 蔬菜食用频率为6～7和<4 d/周者分别占89.9%(44 019/48 974)和4.6%(2262/48 974),水果食用频率为5～7和<2 d/周者分别占30.8%(15 072/48 974)和31.5%(15 432/48 974).自报COPD患病率为2.9%(1412/48 974).调整了年龄、性别、城乡、被动吸烟和COPD家族史后,与水果食用频率较低(<2 d/周)的人群相比,水果食用频率较高的人群(5～7 d/周)患COPD的风险降低(在不吸烟者中,OR=0.80,95%CI:0.66～0.98;在吸烟者中,OR=0.80,95%CI:0.64～0.99).在不吸烟者中,高蔬菜食用频率(6～7 d/周)者患COPD风险较低(OR=0.65,95%CI:0.48～0.89).结论 食用蔬菜和水果可能对COPD有保护性作用.

Abstract：

Objective To explore the association between frequency of fruit and vegetable intake and chronic obstructive pulmonary disease(COPD).Methods In 2007,48 974 Chinese residents aged 15-69 years were selected as study participants by multistage stratified proportionate to size random sampling from the 161 sites of Disease Surveillance Points System.Standardized questionnaires were used to collect relevant information to compare the risk for self-reported physician diagnosed COPD between different frequency groups for fruit(<2,2-4,5-7 d/week) and vegetable(<4,4-5,6-7 d/week) intake.Results The proportion of vegetable intake was 89.9%(44 019/48 974) and 4.6%(2262/48 974) for individuals with frequency of 6-7 and <4 d/week respectively.The proportion of fruit intake was 30.8%(15 072/48 974) and 31.5%(15 432/48 974) for individuals with frequency of 5-7 and <2 d/week respectively.The prevalence of self-reported COPD was 2.9%(1412/48 974).After adjusting for age,sex,urban/rural areas,passive smoking exposure and family history,the risk of COPD decreased among those with high frequency(5-7 d/week) of fruit intake( OR=0.80,95%CI:0.66-0.98 for never smokers; OR=0.80,95%CI:0.64-0.99 for ever smokers),compared to subjects with low frequency of fruit intake(<2 d/week).Among never smokers, those with high frequency of vegetable intake(6-7 d/w) had a low risk of developing COPD (OR=0.65,95%CI:0.48-0.89).Conclusion There were beneficial effects of fruit and vegetable intake on COPD.

Association between frequency of fruit and vegetable intake and chronic obstructive pulmonary disease

Objective To explore the association between frequency of fruit and vegetable intake and chronic obstructive pulmonary disease(COPD).Methods In 2007,48 974 Chinese residents aged 15-69 years were selected as study participants by multistage stratified proportionate to size random sampling from the 161 sites of Disease Surveillance Points System.Standardized questionnaires were used to collect relevant information to compare the risk for self-reported physician diagnosed COPD between different frequency groups for fruit(<2,2-4,5-7 d/week) and vegetable(<4,4-5,6-7 d/week) intake.Results The proportion of vegetable intake was 89.9%(44 019/48 974) and 4.6%(2262/48 974) for individuals with frequency of 6-7 and <4 d/week respectively.The proportion of fruit intake was 30.8%(15 072/48 974) and 31.5%(15 432/48 974) for individuals with frequency of 5-7 and <2 d/week respectively.The prevalence of self-reported COPD was 2.9%(1412/48 974).After adjusting for age,sex,urban/rural areas,passive smoking exposure and family history,the risk of COPD decreased among those with high frequency(5-7 d/week) of fruit intake( OR=0.80,95%CI:0.66-0.98 for never smokers; OR=0.80,95%CI:0.64-0.99 for ever smokers),compared to subjects with low frequency of fruit intake(<2 d/week).Among never smokers, those with high frequency of vegetable intake(6-7 d/w) had a low risk of developing COPD (OR=0.65,95%CI:0.48-0.89).Conclusion There were beneficial effects of fruit and vegetable intake on COPD.