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| 原发性巨球蛋白血症15例 | |
| 引用本文： | 王莉,徐卫,仇红霞,李建勇. 原发性巨球蛋白血症15例[J]. 白血病．淋巴瘤, 2008, 17(6): 433-435 |
| 作者姓名： | 王莉 徐卫 仇红霞 李建勇 |
| 作者单位： | 南京医科大学第一附属医院,江苏省人民医院血液科,南京,210029;南京医科大学第一附属医院,江苏省人民医院血液科,南京,210029;南京医科大学第一附属医院,江苏省人民医院血液科,南京,210029;南京医科大学第一附属医院,江苏省人民医院血液科,南京,210029 |
| 摘 要： | 目的探讨原发性巨球蛋白血症（WM）的临床特点。方法回顾性分析15例患者临床表现、免疫表型及治疗。结果3例完全缓解（CR），9例部分缓解（PR），7例生存，病程最长达79个月。结论WM传统的诊断方法不够完善，免疫表型能够更进一步明确诊断。在治疗方面，WM是不能治愈性疾病，但经积极治疗生存期可延长，应考虑化疗并血浆置换联合治疗。 |
| 关 键 词： | Waldenstrom 巨球蛋白血症 诊断 治疗 |
| 收稿时间： | 2007-09-12; |
Clinical analysis of 15 patients with Waldenstrom's macroglobulinemia |
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| WANG Li,XU Wei,QIU Hong-xia,LI Jian-yong. Clinical analysis of 15 patients with Waldenstrom's macroglobulinemia[J]. Journal of Leukemia & Lymphoma, 2008, 17(6): 433-435 | |
| Authors: | WANG Li XU Wei QIU Hong-xia LI Jian-yong |
| Affiliation: | WANG Li, XU Wei, QIU Hong-xia, LI Jian-yong. (Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province People＇s Hospital, Nanjing 210029, China) |
| Abstract: | Objective To investigate the diagnosis and treatment of Waldenstrom's macrogiobulinemia(WM).Methods The clinical information of 15 patients with WM were analyzed retrospectively.Results 3 cases had achieved complete response(CR).9 cases had achieved partial response(PR).7 cases remained alive,one of them lived beyond 79 months.Conclusion The traditional diagnosis of WM is not enough,and immunophenotype described for WM diagnosis is more important.WM is an incurable disease.Treatment with plasmapheresis and chemotherapy appears highly effective and safe for WM. |
| Keywords: | Waldenstrom macroglobulinemia Diagnosis Therapy |
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