多普勒超声评价慢性二尖瓣返流左室舒张功能

用脉冲多普勒超声技术对１８例慢性二尖瓣返流（ＣＭＲ）患者和２１例正常人进行二尖瓣舒张期血流频谱定量研究。结果表明，ＣＭＲ出现的假性正常的二尖瓣血流频谱，掩盖了左室舒张功能减退，实际为左室松驰功能障碍及顺应性降低所致。ＣＭＲ组的Ｅ波压差（Ｅ－ＰＧ）、Ａ波压差（Ａ－ＰＧ）、等容舒张时间（ＩＶＲＴ）、Ｅ波减速时间（Ｅ－ＤＴ）及左室充盈时间．（ＬＶＦ）等与正常对照组比较有显著性差异（Ｐ＜０．０１），是ＣＭＲ情况下反映左室舒张功能减退的综合评价指标。

Quantitative Evaluation of the Left Ventricle Diastolic Function in Chronic Mitral Regurgitation by Pulsed Wave Doppler Echocardiography

Pulsed wave Doppler echocardiograpdy was performed in eighteen cases with chronic mitral regurgitation (CMR) and 21 normal individuals to detect the quantitative changes of the mitral diastolic flow spectrum. The results showed that the pseudonormalization of mitral flow spectrum in CMR was actually caused by impaired left ventricle (LV) active relaxation and decreased LV compliance; It thus masked the LV diastolic dysfunction in CMR. E-wave pressure gradiant (E-PG),A-wave pressure gradiant (A-PG),isovolumic relaxation time (IVRT),E deceleration time (E-DT) and LV filling time (LVFT) in CMR group were significantly different in from those in normal group (P<0. 01).Therefore it is essential to integrate these parameters as the indexes to evaluate the LV diastolic dysfunction in CMR.