| 高渗氯化钠羟乙基淀粉40注射液抗失血性休克临床观察 |
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| 引用本文： | 孟德胜,郭晓丽,马晓林,蹇华胜,傅若秋,吴畏,葛衡江,陈亮,蒋耀光. 高渗氯化钠羟乙基淀粉40注射液抗失血性休克临床观察[J]. 中国医院用药评价与分析, 2002, 2(5): 291-292 |
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| 作者姓名： | 孟德胜 郭晓丽 马晓林 蹇华胜 傅若秋 吴畏 葛衡江 陈亮 蒋耀光 |
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| 作者单位： | 第三军医大学大坪医院,重庆市,400042 |
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| 摘 要： | 目的:考察高渗氯化钠羟乙基淀粉40注射液(HSS40)抗休克作用的剂量范围,并对其临床疗效和安全性进行初步观察.方法:以失血性休克患者为受试对象,观察静脉滴注HSS40后受试者血压变化和实验室检查指标的变化。结果:应用HSS40在500ml范围内可迅速升高血压,有效率为100％.;部分受试者血氯、血钠水平有一过性升高,给药后24小时恢复正常结论:HSS40在剂量为80ml～500ml范围内,安全有效,推荐临床用药剂量为300ml～500ml
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| 关 键 词： | 高渗氯化钠羟乙基淀粉40注射液 失血性休克 临床观察 |
| 文章编号： | 2002-05-0291-02 |
| 修稿时间： | 2002-07-04 |
The Clinical Study of Hypertonic Sodium Chloride Hydroxylethyl Starch 40 Injection on Anti-hemorrha_gic Shock |
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| MENG Desheng,GUO Xiaoli,MA Xiaolin,JIAN Huasheng,FU Ruoqiu,WU Wei,GE Hengjiang,CHEN Liang,JIANG Yaoguang. The Clinical Study of Hypertonic Sodium Chloride Hydroxylethyl Starch 40 Injection on Anti-hemorrha_gic Shock[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2002, 2(5): 291-292 |
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| Authors: | MENG Desheng GUO Xiaoli MA Xiaolin JIAN Huasheng FU Ruoqiu WU Wei GE Hengjiang CHEN Liang JIANG Yaoguang |
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| Abstract: | OBJECTIVE: To survey the dosage range, clinical effect and safely of hypertonic sodium chloride hydroxylethyl starch 40 injection(HSS40) on anti - hemorrhagic shock .METHODS:The changes of blood pressure and laboratory examination indices were detected after HSS40 was infused into the patients who suffered from hemorrhagic shock.RESULTS: HSS40 could rapidly raise the blood pressure in a dose below 500ml and the effective rate could reach 100% .In part of patients,the levels of serum Cl - and Na increased temporarily and restored after 24 hours.CONCLUSION: HSS40 was safe and effective in doses of 80ml - 500ml. The clinical doses of 300ml- 500ml are recommended. |
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| Keywords: | hypertonic sodium chloride hvdroxvlethyl starch 40 injection hemorrhagic shock clinical observation |
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