| 蒙脱石散防治阿奇霉素胃肠道不良反应的临床观察 |
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| 引用本文： | 张元明. 蒙脱石散防治阿奇霉素胃肠道不良反应的临床观察[J]. 儿科药学杂志, 2009, 15(6): 49-51 |
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| 作者姓名： | 张元明 |
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| 作者单位： | 江苏省泰州市中医院,江苏泰州,225300 |
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| 摘 要： | 目的:观察蒙脱石散防治阿奇霉素胃肠道不良反应的效果.方法:观察2007年10月～2008年12月我院儿科门诊应用阿奇霉素治疗呼吸道感染患儿150例,其中80例加用蒙脱石散口服为观察组,另70例不加蒙脱石散为对照组.结果:观察组胃肠道不良反应发生率为3.75%,对照组胃肠道不良反应发生率为12.86%,两组比较差异有统计学意义(χ2=4.21,P<0.05).对照组轻度不良反应5例,重度不良反应4例,因不良反应停药4例,停药率5.71%;观察组轻度不良反应2例,重度不良反应1例,因不良反应停药1例,停药率1.25%.结论:蒙脱石散具有较好的防治阿奇霉素静滴过程中胃肠道反应的作用,值得临床推广应用.
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| 关 键 词： | 阿奇霉素 蒙脱石散 胃肠道 不良反应 |
Clinical Observation of Smectite Powder in Preventing or Treating the Gastrointestinal Adverse Reaction Caused by Azithromycin |
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| ZHANG Yuan-ming. Clinical Observation of Smectite Powder in Preventing or Treating the Gastrointestinal Adverse Reaction Caused by Azithromycin[J]. Journal of Pediatric Pharmacy, 2009, 15(6): 49-51 |
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| Authors: | ZHANG Yuan-ming |
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| Affiliation: | ZHANG Yuan-ming( Taizhou Hospital of Traditional Chinese Medicine,Jiangsu Province,Jiangsu Taizhou 225300,Ghina ) |
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| Abstract: | Objective:To investigate the prophylaxis and treatment of Smectite Powder on azithromycin caused gastrointestinal adverse effects.Methods:One hundred and fifty pediatric outpatients were observed with respiratory infection from October 2007 through December 2008 in our hospital in the treatment of Azithromycin,among which 80 cases taking Smectite powder orally in addition to the control group,and the other 70 cases for the control group not.Results:The incidence rate of gastrointestinal adverse reactions in... |
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| Keywords: | Azithromycin Smectite powder Gastrointestinal Adverse effects |
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