13898例住院围产儿出生缺陷监测结果分析

目的:统计住院围产儿出生缺陷的发生情况及影响因素,寻找预防出生缺陷的措施。方法:收集2006年1月1日～2011年12月31日福建省新生儿救护中心厦门分中心住院围产儿13 898例中发生出生缺陷的临床资料,对患儿出生缺陷构成状况、孕妇多种相关因素进行回顾性分析。结果:6年间福建省新生儿救护中心厦门分中心住院患儿出生缺陷发生率为22.45‰(312/13 898)。出生缺陷按不同组织器官及部位划分,位于前5位依次为心血管系统、四肢畸形、肾脏发育异常、尿道下裂、颌面部畸形。结论:大力实施围产期新生儿出生缺陷监测与干预工作,积极开展围产保健、避免早孕期高危因素的暴露、提高产前筛查和诊断技术对降低出生缺陷发生率有指导意义。

Analysis of the monitoring resurlts of birth defects of 13898 perinatal infants

Objective:To compile the prevalence and factors of birth defects on hospital perinatal infants,and to search for countermeasures of preventing and controlling birth defects. Methods:Data of birth defects of 13.898 perinatal infants hospitalized in our hospital from January 1,2006 to December 31,2011 were reviewed.Types of birth defects and prenatal risk factors were retrospectively analyzed. Results:The prevalence rate of birth defects on hospitalized perinatal infants over the past 6 years was 22.45 per 1 000(312/13 898).Differentiated by system and location,the top five birth defects were congenital heart disease,congenital malformations of limb,dysplastic kidney,hypospadias,maxillofacial deformity. Conclusion:The surveillance and intervention program of birth defects shall be performed.Strengthening health care during pregnancy,avoiding risk factor exposure during the first trimester of pregnancy,enhancing prenatal screening and diagnosis technology are significant in decreasing the rate of birth defects.