老年人呼吸道衣原体感染的研究

目的探讨老年人呼吸道衣原体感染的状况。方法采用放线菌酮处理的Ｈｅｌａ２２９细胞、单克隆抗体免疫荧光对健康老年组、老年呼吸道感染组及肺部肿瘤组的咽拭子及纤维支气管镜标本进行了衣原体的分离培养鉴定。结果健康老年组６６例的咽拭子标本中均未分离到衣原体。呼吸道感染组１３５保做了沙眼在原体分离，７例阳性，阳性率为５．１８％；其中１１３例亦做了肺炎衣原体分离，也有７例阳性，阳性率为６．１９％；而１１３例标本中均未检出鹦鹉热衣原体。４２例肺部肿瘤患者的上述３种衣原体检出的结果分别为沙眼衣原体阳性率１１．９０％（４２例中５例阳性），肺炎衣原体阳性率为１４．２８％（２１例中３例阳性），２１例标本中均未检出鹦鹉热衣原体。结论肺炎衣原体和沙眼衣原体均可能是老年人呼吸道感染的重要病原因之一，对老年人肺部肿瘤患者呼吸道衣原体感染亦应引起重视

A study on chlamydia infection in the aged

Objective To study chlamydia infection in the aged. Method Isolation of chlamydia from specimens of throatswabs and bronchoscopic swabs were done by using cycloheximids-treated Hela 229 cells and detected by monoclonal antibody immunofluorescence in normal aged,aged with respiratory infections and lung tumors.Results The isolation rates of chlamydia pneumonia(Cpn),chlamydia trachomatis(CT),and chlamydia psittain(CP) from the respiratory infections were 6.19%(7/113),5.18% (7/135),0%(0/113) and the isolation rates of Cpn.CT and CP from the lung tumour were 14.28%(3/21),11.90%(5/42) and 0%(0/21).Conclusions Our results suggest that the Cpn and CT are important pathogens in aged with respiratory infections including the lung tumour.