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| 弥漫大B细胞淋巴瘤的治疗进展 | |
| 引用本文： | 张利娟,王凤玮. 弥漫大B细胞淋巴瘤的治疗进展[J]. 中华临床医师杂志(电子版), 2014, 0(11): 130-135 |
| 作者姓名： | 张利娟 王凤玮 |
| 作者单位： | 天津市人民医院肿瘤科,300121 |
| 摘 要： | 弥漫大B细胞淋巴瘤是非霍奇金淋巴瘤中最常见的一种类型,也是发生在成人淋巴瘤中最常见的一种类型。其在临床表现、形态学、免疫表型、细胞遗传学、分子生物学、对化疗的反应及预后上都表现出明显的异质性。随着诊断医学的发展和新的药物的开发和应用,弥漫大B细胞淋巴瘤在诊断和治疗方面取得一些进展,特别是在免疫组化的分类和嵌合抗CD20单克隆抗体利妥昔单抗联合治疗方面,使弥漫大B细胞淋巴瘤在疗效和预后得到了很大的改善。 |
| 关 键 词： | 淋巴瘤,大B细胞,弥漫性 临床特点 形态学 诊断 治疗 |
Progress of diffuse large B cell lymphoma |
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| Zhang Lijuan,Wang Fengwei. Progress of diffuse large B cell lymphoma[J]. Chinese Journal of Clinicians(Electronic Version), 2014, 0(11): 130-135 | |
| Authors: | Zhang Lijuan Wang Fengwei |
| Affiliation: | . (Department of Oncology, Tianjin Union Medicine Center, Tianjin 300121, China) |
| Abstract: | Diffuse large B cell lymphoma （DLBCL） is the most common histology of non-Hodgkin lymphoma. It is also the most common type of lymphoma occuring in adult and showed significant heterogeneity on clinical presentation, sign, syndrome, morphology, immun-ophenotype, cytogenetics, molecular biology, response to chemotherapy and prognosis. With the development of diagnostic techniques and application of new drugs in the diagnosis and treatment of DLBCL had made some progress. Especially in the the classification of immuno-histochemistry and chimeric anti-CD20 monoclonal antibody of rituximab＇s emergence, that made a great improvement in the efficacy and prognosis. |
| Keywords: | Lymphoma, large B-cell, diffuse Clinical feature Morphology Diagnosis Treatment |
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