耐甲氧西林金黄色葡萄球菌医院感染研究进展

抗生素的大量应用,以及新的广谱抗生素的不断问世,致使细菌耐药性日趋严重,已经成为世界关注的公共卫生问题。医院感染的重要病原菌-耐甲氧西林金黄色葡萄球菌(MRSA)临床感染十分常见,因其表现为多重耐药,易引起感染的暴发流行,是临床治疗非常棘手的一大难题和研究热点。MRSA医院感染严重,社区获得性MRSA感染也有增加的趋势而备受关注。且国外已经出现耐万古霉素的金黄色葡萄球菌(VRSA),被称为超级细菌(Superbug)或沉默的杀手(Sillent killer)。本文论述了MRSA医院感染的研究进展及其防治。

Progress in research of nosocomial infection of methicillin-resistant Staphylococcus aureus

The wide use of antibiotics and development of new broad-spectrum antibiotics have resulted in serious drug resistance of bacteria,which is one of the important public health problems in the globe.Nosocomial infection of methicillin-resistant Staphylococcus aureus(MRSA) is common and duo to its multi drug resistance and proneness to spread,the treatment of MRSA infection is diffucult.Not only the nosocomial infection of MRSA infection is seriuos,but also the community acquired infection of MRSA is in increase.Vancomycin-resistant Staphylococcus aureus(VRSA) has emerged in foreign countries,which is called super-bacteria(Superbug) or silent killer.This paper summerizes the progress in the research of the nosocomial infection of MRSA and in the prevetnion and treatment of MRSA infection.