| 幽门螺杆菌粪便抗原检测方法学评价 |
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| 作者姓名： | Guo JX Han J Chen L Xu J Liu J Zhao J Liu AX Yang LH Song YJ Li BA Mao YL |
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| 作者单位： | 1. 中国人民解放军第三○二医院临检中心,北京,100039
2. 中国人民解放军第三○二医院肝硬化诊疗中心,北京,100039 |
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| 摘 要： | 目的 评价幽门螺杆菌粪便抗原（ HpSA）检测在诊断患者幽门螺杆菌（Hp）感染中的价值.方法 以胃镜病理学诊断结果为金标准,对328例有消化道症状患者粪便,同时应用酶联免疫吸附实验检测幽门螺杆菌粪便抗原,计算HpSA检测诊断Hp感染的特异性、灵敏度和准确性等性能指标.结果 幽门杆菌粪便抗原酶免疫检测法对Hp感染诊断与金标准相比无统计学差异（P＞0.05）,其敏感性为94.6％、特异性为96.9％、准确性为96.3％、阳性预期值为89.7％、阴性预期值为98.4％.结论 幽门螺杆菌粪便抗原酶免疫检测是一种简便、易行、准确性高、便宜、易重复的非侵入性检测方法.
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| 关 键 词： | 螺杆菌 幽门 诊断 胃镜检查 |
Evaluation of the Helicobacter pylori stool antigen test |
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| Guo JX,Han J,Chen L,Xu J,Liu J,Zhao J,Liu AX,Yang LH,Song YJ,Li BA,Mao YL.Evaluation of the Helicobacter pylori stool antigen test[J].Chinese Journal of Experimental and Clinical Virology,2011,25(6):495-496. |
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| Authors: | Guo Jing-Xia Han Jun Chen Lin Xu Jun Liu Jia Zhao Jing Liu Ai-Xia Yang Li-Hua Song Yong-Ji Li Bo-An Mao Yuan-Li |
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| Institution: | Center of Clinical Laboratory, The No. 302 Hospital of The PLA, Beijing 100039, China. |
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| Abstract: | Objective To evaluate the clinical value of an enzyme-linked immunosorbent assay by the Helicobacter pylori stool antigen ( HpSA ) test for the detection of H.pylori infection.Methods 328 patients were measured upper gastrointestinal endoscopic examination which as gold standards and HpSA test in the meantime,comparing accuracy,sensitivity,specificity and other Indicators.Results In the diagnosis of Hp infection,HpSA test had no significant difference comparing with gold standards and had a P value of over 0.5.The sensitivity of HpSA test was 94.6 ％,while the specificity,veracity,expected positive value,and expected negative value were 96.9 ％,96.3 ％,89.7％ and 98.4％,respectively.Conclusion The H.pylori stool antigen test is a simple,non-invasive method for accurate diagnosis of H.pylori infection. |
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| Keywords: | Helicobacter pylori Diagnosis Gastroscopy |
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