1307例育龄妇女血清TORCH抗体定量检测结果分析

目的 了解昆明地区育龄妇女弓形虫（TOX）、风疹病毒（RV）、巨细胞病毒（CMV）、单纯疱疹病毒（ HSV）,总称为TORCH的感染状况,为预防妊娠TORCH感染、降低新生儿出生缺陷发生率提供参考资料。方法 采用德国virion/serion酶联免疫吸附试验（ELISA）定量试剂,对1307例育龄妇女血清TORCH感染特异性IgM及IgG抗体进行检测,并对其结果进行分析。结果 1307例育龄妇女TORCH感染特异性IgM抗体总阳性率为1.45％,其中TOX：2.83％;RV：2.37％;CMV：0.46％;HSV：2.45％。特异性IgG抗体总阳性率为63.60％,其中TOX：3.98％;RV：72.30％;CMV：97.78％;HSV：80.34％。不同孕期妇女TORCH感染特异性抗体检出率差异无统计学意义。结论 本次调查中,1307例育龄妇女存在一定比例的TORCH现症感染,建议妊娠妇女尽可能进行TORCH筛查,以便尽早采取相应措施,避免由TORCH感染导致出生缺陷发生。

Detection the serum IgM and IgG specific for TORCH in 1307 women in the period of pre-pregnancy and pregnancy

Objective The objective is to obtain the information of women in the period of prepregnancy and pregnancy infected by TORCH (Toxoplasma, Rabella Virus, Cytomegalovirus, and Herpes Simplex Virus) in Kunming for preventing fetus from infection by TORCH in uterus. Methods The serum IgM and IgG specific for TORCH from 1307 women in the period of pre-pregnancy and pregnancy were measured with ELISA and The reagent is the product of virion/serion. Results The serum IgM specific for TORCH were detected in 2. 83％ of 1307 pregnant women for Toxoplasma, 2.37％ for Rebulla Virus,0. 46％ for Cytomegalovirus,2. 45％ for Herpes Simplex Virus. The total positive rate of serum IgM specific for TORCH was 1.45％. The serum IgG specific for TORCH were detected in 3.98％ of 1307 pregnant women for Toxoplasma, 72. 3％ for Rebulla Virus, 97.78％ for Cytomegalovirus, 80. 34％ for Herpes Simplex Virus. The total positive rate of serum IgG specific for TORCH was 63.60％. There was no significant difference among the women with different pregnant situation in terms of the serum IgM and IgG specific for TORCH. Conclusion There are some of women in the period of pre-pregnancy and pregnancy with current infection by TORCH in Kunming. It is recommended to screen for infection by TORCH in women in the period of pre-pregnancy and pregnancy to prevent fetus from infection by TORCH in uterus.