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白芍总甙对白细胞介素-2产生的影响
引用本文:魏伟,梁君山,周爱武,陈敏珠,徐叔云. 白芍总甙对白细胞介素-2产生的影响[J]. 中国药理学通报, 1989, 0(3)
作者姓名:魏伟  梁君山  周爱武  陈敏珠  徐叔云
作者单位:安徽医科大学临床药理研究所 安徽医科大学临床药理研究所 合肥
摘    要:
白芍总甙(0.5~62.5mg/L)对ConA(3mg/L)诱导的大鼠脾细胞产生白细胞介素-2具有双向调节作用。同时用活化小鼠脾细胞检测了ConA诱导大鼠脾细胞产生白细胞介素-2的纯度,表明,主要以白细胞介素-2为主。

关 键 词:白芍总甙  白细胞介素-2  免疫调节

EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION
Wei Wei,Liang Junshan Zhou Aaiwu et al. EFFECTS OF TOTAL GLUCOSIDES OF PAEONY ON INTER-LEUKI'N 2 PRODUCTION[J]. Chinese Pharmacological Bulletin, 1989, 0(3)
Authors:Wei Wei  Liang Junshan Zhou Aaiwu et al
Abstract:
Effects of total glucosides of paeony ( TGP) on interleukin2 ( IL-2 ) production were studied with lL-2-dependent marine splenic lymohocytes. The results showed that IL-2 production by splenocytes was enhanced with low concentration of TGP (0.5-12.5 mg/L) , and diminished over the rang of 12.5-62.5mg/L. The concentration-effect curve seems to be bell-shaped. The data suggested that TGP hap two-sided regulatory effects on IL 2 production by splenocytes.
Keywords:Total glucosides of paeony  Interleukin 2  Splenocytes
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