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| 三七总皂甙在大鼠肝脏缺血再灌注损伤中肝细胞超微结构的保护作用 | |
| 引用本文： | 元文勇,姜文泉,姜惟龙,申瑢硕. 三七总皂甙在大鼠肝脏缺血再灌注损伤中肝细胞超微结构的保护作用[J]. 中国误诊学杂志, 2003, 3(11): 1618-1620 |
| 作者姓名： | 元文勇 姜文泉 姜惟龙 申瑢硕 |
| 作者单位： | 1. 新乡医学院第一附属医院普通外科,河南,卫辉,453100 2. 延边大学医学院附属医院普通外科,吉林,延吉,133000 |
| 摘 要： | 目的：观察三七总皂甙对大鼠肝脏缺血再灌注损伤的保护作用。方法：通过阻断血运前将PNS经直接通道注入并保留于肝脏组织的方法，电镜下观察肝细胞超微结构的病理变化过程。结果：电镜观察表明PNS组超微结构的破坏较对照组轻。结论：PNS具有减轻和预防大鼠缺血再灌注肝细胞核、线粒体等超微结构损伤的作用。 |
| 关 键 词： | 三七总皂甙 药理学 大鼠 肝细胞 超微结构 缺血再灌注损伤 保护作用 |
| 文章编号： | 1009-6647(2003)11-1618-03 |
| 修稿时间： | 2003-08-01 |
The Protective Role of Total Saponins of Panax Notognseng to the Super-microstructure in Rat Hepatocyte during Ischemia Reperfusion Injury |
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| YUAN Wen-yong,JIANG Wen-quan,JIANG Wei-long,et al.. The Protective Role of Total Saponins of Panax Notognseng to the Super-microstructure in Rat Hepatocyte during Ischemia Reperfusion Injury[J]. Chinese Journal of Misdiagnostics, 2003, 3(11): 1618-1620 | |
| Authors: | YUAN Wen-yong JIANG Wen-quan JIANG Wei-long et al. |
| Abstract: | Objective:To observe the protective role of total saponins of panax notognseng to rat hepatocyte during ischemia reperfusion injury. Methods:PNS was directly injected into liver tissue and was kept there by blocking pro-tal vein and hepatic artery, and the pathologic changes of the hepatocyte super-micro structure was observed by electron microscope. Results:The pathologic changes of super-microstructure in the experimental group were less than thost in the control group. Conclusion: PNS had the function of relieving and preventing rat liver super-microstructure such as nucleus and mitochondrion from ischemia reperfusion injury. |
| Keywords: | Sanchinoside/pharmacology RatsiLiver/ultrastructure(Reperfusion/injury |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |