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慢性肾衰Lp(a)检测的临床意义
引用本文:朱国贞,舒言. 慢性肾衰Lp(a)检测的临床意义[J]. 中国临床医学, 2002, 9(2): 112-113
作者姓名:朱国贞  舒言
作者单位:1. 山西医科大学第二医院肾内科,太原,03001
2. 武警8650部队医院,榆次,030608
摘    要:目的:探讨脂蛋白(a)[Lp(a)]检测在慢性肾衰患者中的临床意义。方法:取60例慢性肾衰患者及30例正常人空腹肘静脉血,采用免疫比浊法测定血清Lp(a)含量。按血肌酐(Cr)水平及年龄段分组。结果:慢性肾衰患者Lp(a)含量显著高于正常对照组(P<0.05),Lp(a)水平与鉴别、年龄、血肌酐水平无关。结论:Lp(a)作为一种肾毒性物质,可存在于较早期慢性肾衰患者中,Lp(a)检测有助于评估慢性肾衰患者心血管事件的危险性。

关 键 词:慢性肾功能衰竭 脂蛋白(a) 心血管事件 检测

Clinical Significance of Lp(a) in Patients with Chronic Renal Failure
Zhu Guozhen Shu Yan. Clinical Significance of Lp(a) in Patients with Chronic Renal Failure[J]. Chinese Journal Of Clinical Medicine, 2002, 9(2): 112-113
Authors:Zhu Guozhen Shu Yan
Abstract:Objective: To study the clinical significance of Lp(a) in patients with chronic renal failure(CRF). Methods: Lp (a) was measured with turbidimetric immunoassay in 60 CRF patients and 30 normal controls. Lp(a) values were compared by age, sex and levels of creatinine. Results: There was a significant increase in Lp(a) in patients with CRF compared to the con-trols. The correlations between Lp(a) and age, sex, the level of creatinine were not significant. Conclusion: Lp(a) may serve as an indicator of patients with CRF, even those in the early stages. The increasing serum level of Lp(a) may be the risk factor of cardiovascular events.
Keywords:Chronic renal failure Lipoprotein(a)
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