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HPLC法测盐酸头孢吡肟精氨酸中头孢吡肟的含量
引用本文:郭玉英,岳志萍. HPLC法测盐酸头孢吡肟精氨酸中头孢吡肟的含量[J]. 黑龙江医药, 2006, 19(5): 338-338
作者姓名:郭玉英  岳志萍
作者单位:哈药集团制药总厂,150086;哈药集团制药总厂,150086
摘    要:
目的:用高效液相色谱法测定头孢吡肟含量。方法:ODS柱,以戊烷磺酸钠溶液-乙腈为流动相,于254nm波长处检测,流速为1.0ml/min。结果:该方法在80μg·ml-1-480μg·ml-1范围内峰面积与浓度呈良好的线性关系(r=0.9997),重复性实验RSD=0.59%,n=5。结论:方法简便,快速,重复性好。

关 键 词:高效液相色谱  头孢吡肟  含量
文章编号:1006-2882(2006)05-338-01
收稿时间:2005-12-21
修稿时间:2005-12-21

Determination of the content of Cefepime in Cefepime Dihydrochloride and Arginine by HPLC
Guo Yuying,Yue Zhiping. Determination of the content of Cefepime in Cefepime Dihydrochloride and Arginine by HPLC[J]. Heilongjiang Medicine, 2006, 19(5): 338-338
Authors:Guo Yuying  Yue Zhiping
Abstract:
Objective: To determinine the content of the Cefepime by HPLC. Methods: the mobile phase of DHNaOS. HO-CHCN was pumped at 1.0ml/min with an CDS column, the detector was 215nm. Results: standard curve of peak area and concentration was linear in the concentration range Conclusion: This method has aproperty of simple, rapid sensitive and reproducible.
Keywords:Cefepime Dihydrochloride  HPLC  content
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