| 老年人认知功能与白质异常相关性的MR扩散张量成像研究 |
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| 引用本文： | 张琳,郑林丰,张贵祥,王夕富,胡运胜,凌茹晶.老年人认知功能与白质异常相关性的MR扩散张量成像研究[J].中国医学计算机成像杂志,2011,17(1):12-17. |
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| 作者姓名： | 张琳 郑林丰 张贵祥 王夕富 胡运胜 凌茹晶 |
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| 作者单位： | 1. 上海交通大学附属第一人民医院放射科
2. 上海交通大学附属第一人民医院老年科 |
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| 摘 要： | 目的:本研究利用MR扩散张量成像部分各向异性(FA)值,研究老年人的不同水平认知功能和脑白质异常的相关性,并探讨脑内微静脉改变的意义.方法:正常认知功能(CN)组13例,轻度认知功能障碍(MCI)组12例,痴呆组10例.采用简易智能状态量表(MMSE)、临床痴呆量表(CDR)、总体衰退量表(GDS)和日常生活活动能力量...
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| 关 键 词： | 扩散张量成像 部分各向异性 磁共振成像 认知功能 老年 |
MR Diffusion Tensor Imaging of White Matter Abnormality: Correlation with Cognitive Function in Elders |
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| ZHANG Lin,ZHENG Lin-feng,ZHANG Gui-xiang,WANG Xi-fu,HU Yun-sheng,LING Ru-jing.MR Diffusion Tensor Imaging of White Matter Abnormality: Correlation with Cognitive Function in Elders[J].Chinese Computed Medical Imaging,2011,17(1):12-17. |
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| Authors: | ZHANG Lin ZHENG Lin-feng ZHANG Gui-xiang WANG Xi-fu HU Yun-sheng LING Ru-jing |
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| Institution: | ZHANG Lin1,ZHENG Lin-feng1,ZHANG Gui-xiang1,WANG Xi-fu1,HU Yun-sheng1,LING Ru-jing2 1 Department of Radiology,Shanghai Jiaotong University Affiliated First People's Hospital2 Department of Geratology,Shanghai Jiaotong University Affiliated First People's Hospital 100 Haining Rd.,Shanghai 200080,P.R.C. |
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| Abstract: | Purpose:To investigate the relationship between fractional anisotropy(FA) value of diffusion tensor imaging(DTI) and cognitive function in elders,and observe their microvascular changes in white matter.Methods:Subjects were grouped into normal cognition(CN)(13),mild cognitive impairment(MCI)(12) and dementia(10).Neuropsychology tests included mini-mental state examination(MMSE),clinical dementia rating(CDR),global deterioration scale(GDS) and activity of daily living scale(ADL).Total 12 regions of interest ... |
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| Keywords: | Diffusion tensor imaging Fractional anisotropy Magnetic resonance imaging Cognitive function Elders |
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