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| 原发性中枢神经系统淋巴瘤的MRI影像诊断及病理特点 | |
| 引用本文： | 刘玲,肖家和,魏懿,杨雯娟. 原发性中枢神经系统淋巴瘤的MRI影像诊断及病理特点[J]. 中国医学影像学杂志, 2011, 19(1): 43-47,55. DOI: 10.3969/j.issn.1005-5185.2011.01.009 |
| 作者姓名： | 刘玲 肖家和 魏懿 杨雯娟 |
| 作者单位： | 1. 610041,四川成都,四川大学华西医院放射科;695600,云南大理,大理学院附属医院放射科 2. 四川大学华西医院放射科,四川成都,610041 3. 四川大学华西医院病理科,四川成都,610041 |
| 摘 要： | 目的:分析免疫力正常患者的原发性中枢神经系统淋巴瘤(PCNSL)的MRI特征,提高对该病的术前影像诊断。材料和方法:回顾性分析23例经病理证实的PC-NSL的MRI资料和病理资料。结果:23例PCNSL中,单发16例(69.6%),多发7例(30.4%),共41个病灶,幕上39个病灶,幕下2个病灶。78.0%(32/41)病灶平扫T1WI呈等、低信号,T2WI等、稍低信号,较大的病灶中均未见血管流空;增强后70.7%(29/41)病灶呈均匀实质团块状或结节状明显强化,典型的出现"缺口征"、"尖角征",并靠近蛛网膜下腔;9.8%(4/41)病灶出现囊变,可见"硬环征"。病理证实均为B细胞来源非霍奇金淋巴瘤,除1例为Burkitt淋巴瘤,其余均为弥漫性大B细胞淋巴瘤,镜下肿瘤细胞弥漫分布,瘤细胞大小较一致,胞质少,核大,染色质颗粒粗,15例(65.2%)可见瘤细胞围绕血管呈袖套样浸润,所有病例均未见出血、坏死,钙化。结论:PCNSL的病理学基础决定其MRI表现具有一定特征性,典型的病例,常规MRI多可作出正确的诊断,确诊有赖于病理。 |
| 关 键 词： | 淋巴瘤 中枢神经系统 磁共振成像 病理学,临床 |
MRI Diagnosis of Primary Central Nervous System Lymphomas and Pathological Features |
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| LIU Ling,XIAO Jiahe,WEI Yi,YANG Wenjuan. MRI Diagnosis of Primary Central Nervous System Lymphomas and Pathological Features[J]. Chinese Journal of Medical Imaging, 2011, 19(1): 43-47,55. DOI: 10.3969/j.issn.1005-5185.2011.01.009 | |
| Authors: | LIU Ling XIAO Jiahe WEI Yi YANG Wenjuan |
| Affiliation: | LIU Ling XIAO Jiahe WEI Yi YANG Wenjuan Department of Radiology,West China Hospital,Sichuan University,Chendu,Sichuan 610041 |
| Abstract: | Purpose To evaluate MRI manifestations of PCNSL in immunocompetent patients,so as to improve MRI diagnostic accuracy of PCNSL.Materials and Methods The MRI and pathological findings in 23 patients with confirmed PCNSL were retrospectively analyzed.Results 41 lesions were identified in 23 patients,16(69.6%)patients with solitary tumor focus and the other 7(30.4%)presenting a multifocal form up to 25 lesions.39 of 41 lesions located at supratentorial brain,the other two at infratentorial brain.The most freque... |
| Keywords: | lymphoma central nervous system magnetic resonance imaging pathology clinical |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |