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| 理中丸含药血清对Cajal间质细胞的影响 | |
| 引用本文： | 张丰华,黄秀深,罗明凤,孙改侠. 理中丸含药血清对Cajal间质细胞的影响[J]. 浙江中医药大学学报, 2010, 34(1): 44-45 |
| 作者姓名： | 张丰华 黄秀深 罗明凤 孙改侠 |
| 作者单位： | 成都中医药大学,成都,610075 |
| 基金项目： | 四川省教育厅资助项目(No:2005A054)~~ |
| 摘 要： | [目的]探讨理中丸对Cajal间质细胞的作用。[方法]通过体外培养及血清药理学的方法,观察理中丸含药血清对Cajal间质细胞(ICC)Ca2+-ATP酶、琥珀酸脱氢酶(SDH)和乳酸脱氢酶(LDH)活力的影响。[结果]理中丸含药血清能明显提高ICC细胞Ca2+-ATP酶活力(P0.01),使ICC细胞外Ca2+浓度提高(P0.01);并在明显提高ICC细胞内SDH活力的同时(P0.01),降低ICC细胞内LDH活力(P0.01)。[结论]理中丸含药血清能提高ICC细胞Ca2+-ATP酶活力,同时还能增强ICC细胞内的有氧代谢,抑制细胞内的无氧代谢。 |
| 关 键 词： | 理中丸 Ca2＋-ATP酶 琥珀酸脱氢酶 乳酸脱氢酶 |
Effect of Medicated Serum of Lizhong Bolus on ICC |
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| Huang Xiushen Chengdu University of TCM,Sichuan. Effect of Medicated Serum of Lizhong Bolus on ICC[J]. Journal of Zhejiang University of Traditional Chinese Medicine, 2010, 34(1): 44-45 | |
| Authors: | Huang Xiushen Chengdu University of TCM Sichuan |
| Abstract: | [Objective] To explore the effects of medicated serum of Lizhong Bolus on ICC.[Methods] To observe the regulatory effects of medicated serum of Lizhong Bolus on activity of Ca2+-ATPase,SDH and LDH in ICC by the methods of culture in vitro and Serum Pharmacology.[Result]The medicated serum of Lizhong Bolus could obviously improve the activity of Ca2+-ATPase and SDH in ICC(P<0.01)as well as the extracellular Ca2+ concentration;and it could remarkably inhibit the activity of LDH(P<0.01).[Conclusion] The medica... |
| Keywords: | Lizhong Bolus Ca2＋-ATPase Succinate Dehydrogenase（SDH） Lactate Dehydrogenase（LDH） |
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