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Evaluation of the Cepheid Xpert GBS Assay for Rapid Detection of Group B Streptococci in Amniotic Fluids from Pregnant Women with Premature Rupture of Membranes |
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| Authors: | Nadege Bourgeois-Nicolaos Anne-Gael Cordier Christelle Guillet-Caruba Fran?ois Casanova Alexandra Benachi Florence Doucet-Populaire |
| Affiliation: | aService de Bactériologie-Hygiène, Hopital Antoine Béclère, APHP, Université Paris Sud, Clamart, France;bService de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine-Béclère, AP-HP, Université Paris Sud, Clamart, France;cUniversité Paris Sud, EA 4043 USC INRA, Chatenay-Malabry, France |
| Abstract: | The Xpert GBS real-time PCR assay for the detection of group B streptococci (GBS) in antepartum screening samples was evaluated on amniotic fluid samples collected from 139 women with premature rupture of membrane at term. When any intrapartum positive result from the Xpert GBS or culture was considered a true positive, the sensitivities of the Xpert GBS and culture were 92.3% and 84.6%, respectively. This assay could enhance exact identification of candidates for intrapartum antibiotic prophylaxis. |
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