Worrisome Trend of New Multiple Mechanisms of Linezolid Resistance in Staphylococcal Clones Diffused in Italy |
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| Authors: | Floriana Campanile Gino Mongelli Dafne Bongiorno Chiara Adembri Milva Ballardini Marco Falcone Francesco Menichetti Antonella Repetto Carla Sabia Assunta Sartor Claudio Scarparo Carlo Tascini Mario Venditti Federica Zoppi Stefania Stefani |
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| Institution: | aUniversity of Catania, Catania, Italy;bAzienda Ospedaliera Universitaria Careggi, Firenze, Italy;cSan Filippo Neri Hospital, Roma, Italy;dUniversity of Roma La Sapienza, Roma, Italy;eNuovo Ospedale Santa Chiara, Pisa, Italy;fSanta Maria della Misericordia Hospital Perugia, Perugia, Italy;gSanta Maria della Misericordia University Hospital, Udine, Italy;hUniversity of Modena and Reggio, Modena, Italy |
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| Abstract: | In order to assess the frequency of clinically relevant linezolid-resistant staphylococcal isolates, and the role of linezolid in maintaining and coselecting multiple resistance mechanisms (cfr, 23S rRNA, L3/L4 mutations), a prospective Italian study was performed from 2010 to 2011 to confirm the diffusion of three major multidrug-resistant clones (ST2, ST5, ST23). |
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