抗栓药物联合治疗急性脑梗死 |
| |
引用本文: | 钟池,王安宁,宋保华,于新军,逢迎春,张爱娟.抗栓药物联合治疗急性脑梗死[J].中国临床实用医学,2009,3(1):32-34. |
| |
作者姓名: | 钟池 王安宁 宋保华 于新军 逢迎春 张爱娟 |
| |
作者单位: | 山东省潍坊市人民医院神经内科,261041; |
| |
摘 要: | Objective To investigate the efficacy and safety of combinative antithrombotic therapy for patients with acute cerebral infarction who were not eligible for thrombolysis. Methods Eighty-three patients with acute cerebral infarction at six to twelve hours after the onset were randomly allocated into two groups : treat-ment group(n=46) recived batroxobin, aspirin and dipyridamole; control group(n=37) received aspirin. Neuro-logic impairment scole was measured at days 0, and 14. Barthel index of the two groups were observed at days 0 and 90. Blood coagulation action of the treatment group was also measured at days 0,5 and 11. Results In treatment group, the nervous function defect integral examined 14 d after trearment (12.7±6.4 )was markedly decreased than that of control group (20.1±7.2). A remarkable difference (P<0.01 ) was noticed between them. The Barthel index of the treatment group at 90 d after trearment (86.8±12.9 )was markedly increased than that of control group(43.4±15.1 ) (P<0.01 ). The total effective rate of treatment group and control group were 93.5% and 56.8% respectively( P<0.01). Conclusion The efficacy of combinative antithrombotic therapy for patients with acute cerebral infarction who were not eligible for thrombolysis is better than aspirin a-lone. Further more, the risk of bleeding may not increase in combinative antithrombotic therapy.
|
关 键 词: | 急性脑梗死 联合抗栓治疗 巴曲酶 阿司匹林 双嘧达莫 |
Combinative antithrombotic therapy for patients with acute cerebral infarction |
| |
Abstract: | |
| |
Keywords: | Acute cerebral infarctionCombinative antithrombotic therapyBatroxobinAspirinDipyri-damole |
|
|