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新生儿红细胞G-6-PD缺陷症50例临床分析
引用本文:戴缨,余涛,杨涛毅,柳宇红,李炜如.新生儿红细胞G-6-PD缺陷症50例临床分析[J].现代临床医学,2004,30(2):93-94.
作者姓名:戴缨  余涛  杨涛毅  柳宇红  李炜如
作者单位:成都市第三人民医院,四川,成都,610031;四川大学华西第二医院,四川,成都,610041
摘    要:目的:对新生儿红细胞葡萄糖-6-磷酸脱氢酶(G-6-PD)缺陷症进行临床分析.方法:用四氮唑蓝(NBT)定量法测定新生儿红细胞G-6-PD活性.结果:男女发病率有一定差异,男性明显多于女性;男女患者G-6-PD活性、黄疸程度和血红蛋白均值无显著性差异(P>0.05).结论:新生儿红细胞G-6-PD缺陷症的发病可以由感染、氧化性药物、缺氧等因素诱发,也可以没有任何诱因,男女患者在G-6-PD活性、病情程度上没有差异.

关 键 词:新生儿  葡萄糖-6-磷酸脱氢酶  黄疸
文章编号:1671-6051(2004)02-0093-02
修稿时间:2003年12月31日

Neonatal Glucose-6-Phosphate Dehydrogenase Deficiency:50 Cases Report
DAI Ying,YU Tao,Yang Tao-yi,LIU Yu-hong,LI Wei-ru.Neonatal Glucose-6-Phosphate Dehydrogenase Deficiency:50 Cases Report[J].Journal of Modern Clinical Medicine,2004,30(2):93-94.
Authors:DAI Ying  YU Tao  Yang Tao-yi  LIU Yu-hong  LI Wei-ru
Institution:DAI Ying1,YU Tao2,Yang Tao-yi1,LIU Yu-hong1,LI Wei-ru2
Abstract:Objective:To analyze neonatal glucose-6-phosphate dehydrogenase(G-6-PD)deficiency deeply and clinically.Methods:NBT was used to detect activities of G-6-PD.Results:Incidence in male was higher than that in female.The ratio of male to female was 1.78.No differences between male and female in activities of G-6-PD and serum bilirubin and hemoglobin(P>0.05).Conclusion:Neonatal G-6-PD deficiency could induced by infection,oxidation drugs,hypoxia or so,and could happen without any inducement.Difference excited between male and female in incidence but no differences in disease degree and activities of G-6-PD.
Keywords:Neonate  Glucose-6-phosphate dehydrogenase  jaundice
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