An in Vitro Experimental Study on the Antimicrobial Activity of Silicone Oil against Anaerobic Bacteria |
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| Authors: | Ceyhun Arici Cengiz Aras Hrisi Bahar Tokman Muzeyyen Mamal Torun |
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| Affiliation: | 1. Cerrahpasa Medical Faculty, Department of Ophthalmology,;2. Cerrahpasa Medical Faculty, Department of Medical Microbiology, Istanbul University, Istanbul, Turkey,;3. Medical Faculty, Department of Medical Microbiology, Bahcesehir University, Istanbul, Turkey |
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| Abstract: | Purpose: To investigate the in vitro antimicrobial activity of silicone oil against anaerobic agents, specifically Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium.Method: A 0.5 McFarland turbidity of Propionibacterium acnes, Peptostreptococcus spp., Peptostreptococcus anaerobius, Bacteroides fragilis, Fuobacterium spp., and Clostridium tertium was prepared, and 0.1?mL was inoculated into 0.9?mL of silicone oil. Control inoculations were performed in anaerobic blood agar and fluid thioglycollate medium without silicone oil.Results: Propionibacterium acnes retained their viability on the 3rd day in the presence of silicone oil. In total, 9.7?×?106 colonies were enumerated from 1?mL of silicone oil. After a prolonged incubation of 7 days, the number of colonies observed was 9.2?×?106. The other bacteria disappeared after the 3rd day of incubation in silicone oil.Conclusions: Propionibacterium acnes, which is the most common chronic postoperative endophthalmitis agent, is thought to be resistant to silicone oil. |
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| Keywords: | Anaerobic bacteria antimicrobial resistance antimicrobial susceptibility endophthalmitis silicone oil |
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