| 急性缺氧对膈肌疲劳的影响 |
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| 引用本文： | 史依仁,郭先健,赵自强.急性缺氧对膈肌疲劳的影响[J].中国病理生理杂志,1995,11(5):543-546. |
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| 作者姓名： | 史依仁 郭先健 赵自强 |
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| 作者单位： | 重庆第三军医大学新桥医院呼吸中心 |
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| 摘 要： | 本文观察急性缺氧对犬膈肌疲劳的影响，发现急性缺氧条件下，膈肌疲劳的耐受时间为１８．００±３．７０ｍｉｎ，较对照组４１．３３±５．３０ｍｉｎ明显缩短（Ｐ＜０．０５），而且疲劳膈肌恢复过程中产生跨膈压（ｔｒａｎｓｄｉａｐｈｒａｇｍａｔｉｃｐｒｅｓｓｕｒｅ，Ｐｄｉ）明显低于对照组（Ｐ＜０．０５），证实急性缺氧使膈肌疲劳的耐受性明显下降，且不利于疲劳膈肌肌力的恢复。
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| 关 键 词： | 膈肌 疲劳 缺氧 |
Effect of acute hypoxemia on diaphragmatic fatigue |
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| Shi Yi-Ren,Guo Xian-Jian,Zhao Zi-Qiang Xin Qiao Hospitol,Third Military Medical College,Chongqing.Effect of acute hypoxemia on diaphragmatic fatigue[J].Chinese Journal of Pathophysiology,1995,11(5):543-546. |
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| Authors: | Shi Yi-Ren Guo Xian-Jian Zhao Zi-Qiang Xin Qiao Hospitol Third Military Medical College Chongqing |
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| Abstract: | Ten dogs were randomly divided into two groups in order to observe theeffect of acute hypoxemia on canine diaphragmatic fatigue. In hypoxemia group(n=5),diaphragmatic fatigue was produced during hypoxemia while the control group(n=5)was breathing room air.It was found that:1) hypoxemia group had much shorterendurance time than control group;2 )at 60, 120 min after fatigue,the transdiaphrag-matic pressure(Pdi)at all frequency of stimulation in hypoxemia group was less thanthat in control group.It is concluded that acute hypoxemia not only increased the dia-phragmatic fatigue but also delayed the recovery of diaphragmatic fatigue. |
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| Keywords: | Diaphragm Fatigue Anoxemia |
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