原发性高血压与血清C反应蛋白及血脂水平的关系研究

目的探讨原发性高血压与血清c反应蛋白（CRP）和血脂水平的关系。方法186例原发性高血压患者按高血压水平分为A组85例（1级高血压）、B组65例（2级高血压）、C组36例（3级高血压），另选同期健康体检者66例为D组，比较各组CI：IP、总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL—C）、低密度脂蛋白胆固醇（LDL—C）水平。结果A、B、C组CRP、TC、TG、HDL—C、LDL-C水平与D组比较差异均有统计学意义（均P〈0．05），A、B、C三组问各项指标差异均有统计学意义，且三组CRP水平与TG、TC、HDL—C、LDL—C水平有明显相关性（均P〈0．05）。结论高血压水平与患者血清CRP及血脂水平具有明显相关性。

Investigation of relationship between essential hypertension and serum C-reactive protein and plasmad lipid

Objective To investigate the relationship between essential hypertension and serum C-reactive protein and plasma lipids.Methods Detecting fasting serum CRP and plasma lipid in each group of hypertensive patients to investigate the relationship between hypertension and fasting serum CRP and plasma lipids.Results CRP,TC,TG,HDL-C and LDL-C level of A,B and C group had significant differences with that of D group(t =4.03, 4.23, 4.61, 3.12, 3.41, 2.76,2.98,2.56,2.64,2.57,3.05,3.68,2.54,3.16,4.28,all P＜0.05).CRP,TC,TG,HDL-C and LDL-C levels between A,B and C group had significant differences(F = 4.68,4.05,3.29,3.59,4.11,all P＜0.05).There was significant correlation between serum CRP level and TC,TG,HDL-C,LDL-C level in 186 hypertension patients(r =0.274,0.356,0.327,0.302,all P＜0.05).Conclusion CRP,TC,TG and LDL-C levels showed significant linear correlation in patients with hypertension.