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| 慢性鼻窦炎鼻腔黏液中嗜酸粒细胞主要碱性蛋白的表达及意义 | |
| 引用本文： | 侯静,周兵,张罗,李云川,刘铭,魏永祥,黄谦,王洋. 慢性鼻窦炎鼻腔黏液中嗜酸粒细胞主要碱性蛋白的表达及意义[J]. 临床耳鼻咽喉头颈外科杂志, 2008, 22(10): 454-455 |
| 作者姓名： | 侯静 周兵 张罗 李云川 刘铭 魏永祥 黄谦 王洋 |
| 作者单位： | 首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京,100073 |
| 摘 要： | 目的:明确嗜酸粒细胞主要碱性蛋白(MBP)在慢性单纯性鼻窦炎鼻腔黏液中的表达,初步探讨MBP与慢性单纯性鼻窦炎发生的关系.方法:取38例慢性鼻窦炎患者及30例健康人鼻腔黏液,应用酶联免疫吸附法检测嗜酸粒细胞MBP的表达.结果:慢性鼻窦炎患者鼻腔黏液中MBP的表达显著高于对照组(P＜0.01).结论:慢性鼻窦炎鼻腔黏液中MBP表达增加可能是慢性单纯性鼻窦炎发生的原因之一. |
| 关 键 词： | 鼻窦炎,慢性 主要碱性蛋白 |
Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis |
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| HOU Jing,ZHOU Bing,ZHANG Luo,LI Yunchuan,LIU Ming,WEI Yongxiang,HUANG Qian,WANG Yang. Expression and its significance of eosinophil major basic protein in chronic rhinosinusitis[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, 22(10): 454-455 | |
| Authors: | HOU Jing ZHOU Bing ZHANG Luo LI Yunchuan LIU Ming WEI Yongxiang HUANG Qian WANG Yang |
| Abstract: | Objective:To evaluate the expression of eosinophil major basic protein (MBP) in chronic rhinosinusitis (CRS) and discuss the role of MBP in the pathogenesis in CRS.Method:Thirty-eight nasal mucus obtained from CRS patients were used to detect the expression of MBP by Elisa assay. Thirty nasal mucus samples from health people were used as control.Result:The expression of MBP of nasal mucus obtained from CRS patients was obviously higher than that of nasal mucus obtained from control. There was significant statistical difference (P<0.01).Conclusion:MBP was involved in the formation of CRS. |
| Keywords: | Rhinosinusitis chronic Major basic protein |
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