中药汤剂不良反应分析及其评价

目的 :对口服中药汤剂所致的不良反应进行文献调查,以发现其特点。 方法: 检索国内医学文献数据库,收集近30年中药汤剂的不良反应个案报道纳入本次研究。 结果: 中药汤剂不良反应报告数量逐年增加,本研究收集不良反应报道25篇,个案共31例,其中严重不良反应10例,占总数的32.25%。不良反应以过敏反应为主,亦涉及消化系统、神经系统、血液系统等。所有病例经过停药对症治疗均可治愈。 结论: 中药汤剂可以引起药物不良反应,甚至是严重不良反应。判断汤剂中导致不良反应的药物,应采用多种手段综合分析,以提高判断的科学性和准确性。

The analysis and evaluation of Adverse Reactions Caused by TCM Decoction

Objective: To define the present situation of adverse reactions of traditional Chinese medicine (TCM) decoction based on references in recent 30 years. Method: The case reports of adverse reaction caused by TCM decoction were collected from medical literature . Result: The case reports were increased in recent years. Thirty one cases were reported in 25 literatures. In the all cases about 32.25% were severe. The main adverse reaction was allergic reaction. The adverse reaction also happened in digestive system, nervous system and the hematological system. All the patients recovered by withdrawing the decoction and taking symptomatic treatment. Conclusion: TCM decoction can cause adverse reaction, even sometimes cause the severe reaction.Mueti-means and comprehensive analysis can help us to judge the right medicine which bring the adverse reaction and make the judgment more scientifically and accurately.