| 胃乐优对胃粘膜损伤的保护作用 |
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| 引用本文： | 李伟 陈颖莉 杨铭 曲淑岩 王华. 胃乐优对胃粘膜损伤的保护作用[J]. 中药药理与临床, 1995, 11(1): 39-42 |
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| 作者姓名： | 李伟 陈颖莉 杨铭 曲淑岩 王华 |
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| 作者单位： | [1]吉林省中医中药研究院药理室，长春130021 [2]白求恩医科大学第三临床医院制剂室 |
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| 摘 要： | 实验结果表明，胃乐优对大鼠因应激、幽门结扎、无水乙醇及消炎痛等所致胃粘膜损伤均有明显的保护作用。对醋酸性胃粘膜损伤有促进愈合作用。减少胃酸分泌和抑制胃蛋白酶活性可能与其合抑制胃粘膜损伤有关。此外，对醋酸所致小鼠扭体反应有明显的抑制作用。
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| 关 键 词： | 胃乐优 胃粘膜损伤 药物治疗 保护作用 中医药疗法 |
Protective Effect of WeiLeYou on Gastric mucosal lesions |
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| Li Wei, Chen Yengli, Yang Ming, Qu Shuyan. Protective Effect of WeiLeYou on Gastric mucosal lesions[J]. Pharmacology and Clinics of Chinese Materia Medica, 1995, 11(1): 39-42 |
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| Authors: | Li Wei Chen Yengli Yang Ming Qu Shuyan |
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| Abstract: | hen WeiLeYou was administrated orally to rats. it was found that the drug could protect gastric mu-cosal from lesions induced by irritability. pyloroligation . absolute ethanol and indomethacin as well. In addition. it could promote healing of gastric mucosal lesion induced by acetic acid. It was revealed that the drugcould inhibit gastric acid secretion and pepsin activity. and these actions might be related to its anti-ulcer activity. It decreased obviously times of writhing responses induced by acetic acid in mice, indicating it hasanalgesic action. |
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| Keywords: | WeiLeYou Gastric mucosal lesions Gastric acid Pepsin Analgesia |
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