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| 三七止血活血机理的研究Ⅰ．不同剂量三七对小鼠凝血系统的作用 | |
| 引用本文： | 杜力军 何卫世 国月英 马茹. 三七止血活血机理的研究Ⅰ．不同剂量三七对小鼠凝血系统的作用[J]. 中药药理与临床, 1995, 11(3): 25-28 |
| 作者姓名： | 杜力军 何卫世 国月英 马茹 |
| 作者单位： | [1]中国医学科学院用植物研究所，北京l00004 [2]河南新乡市防疫站，453001 [3]中医研究院西苑医院，100091 [4]新乡市中心医院 |
| 摘 要： | 三七粉口服能够抑制小鼠的凝血，并有一定的量效关系，以2．8g／kg．5．6g／kg(相当于成人等效量的4～8倍)时最为明显。这种抗凝血作用主要在内源性凝血系统，并对血小板聚集性有一定的抑制作用(抑制率58．1％)．提示该药所用剂量的大小对于凝血系统有一定的影响。 |
| 关 键 词： | 三七 止血 活血 剂量 小鼠 凝血系统 药理学 |
Hemostasis and Hemoaction of Radix Panax NotoginsengI. Effects of Notoginseng in Different Doses on Mouse''s Blood Coagulation System in Vivo |
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| Du Li inn, He Weishi, Guo Yueying, Ma Ru. Hemostasis and Hemoaction of Radix Panax NotoginsengI. Effects of Notoginseng in Different Doses on Mouse''s Blood Coagulation System in Vivo[J]. Pharmacology and Clinics of Chinese Materia Medica, 1995, 11(3): 25-28 | |
| Authors: | Du Li inn He Weishi Guo Yueying Ma Ru |
| Abstract: | t was showed that the powder of Radix Panax notoginseng (i. g. ) could inhibit the mouse's blood coagulationwith the dose-effect relationship by the experiments of blood coagulation system (BCS). It was the obviously effectsat the dosages of 2.8g/kg and 5.6g/kg (equivalance of 4-8 times adult dose). The action of notoginseng was mainlyon the intrisic coagulation system, also on the platelet aggreegation (inhibiting ratio 58.1%). It is suggested that thedoses of it could affect on BCS. |
| Keywords: | Radix Panax notoginseng blood coagulation system |
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