| 硝苯地平缓释片(I)的释放度差异性研究 |
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| 引用本文： | 郑鹏博,常笑,李金红,边晓丽.硝苯地平缓释片(I)的释放度差异性研究[J].北方药学,2015(2):89-91. |
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| 作者姓名： | 郑鹏博 常笑 李金红 边晓丽 |
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| 作者单位： | 1. 西安交通大学医学部药学院 西安 710061;2. 金花企业 集团 股份有限公司西安金花制药厂 西安 710075 |
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| 摘 要： | 目的：考察硝苯地平缓释片的释放度（I）控制情况。方法：通过不同厂家、不同处方工艺的硝苯地平缓释片（I）和不同仪器的释放度检测结果，反映硝苯地平缓释片（I）释放度的差异性。结果与结论：硝苯地平缓释片释放度检测结果符合质量标准要求，但制剂批的质量一致性有待提高，明确需进行工艺或质量检测方法研究，进行体内外溶出相关性的评价工作。
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| 关 键 词： | 硝苯地平缓释片 释放度 HPMC |
Research of Extended Release Nifedipine Tablets(I) release rate |
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| Zheng pengbo,Chang xiao,Li Jinhong,Bianxiaoli.Research of Extended Release Nifedipine Tablets(I) release rate[J].BEIFANG YAOXUE,2015(2):89-91. |
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| Authors: | Zheng pengbo Chang xiao Li Jinhong Bianxiaoli |
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| Institution: | Zheng pengbo;Chang xiao;Li Jinhong;Bian xiaoli;Department of Medicine,Xi’an Jiaotong University health science center;Golden flower enterprise(group)co,LTD.Xi ’an gold flower pharmaceutical factory; |
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| Abstract: | Objective:Study extended release Nifedipine tablets release control. Methods:Extended Release Nifedipine Tablets(I) detection results of release by different manufacturers, different formulation and different instruments, reflect the Extended Release Nifedipine Tablets (I) status release. Results and Conclusion:Extended Release Nifedipine Tablets release test results meet the quality standards, but the quality consistency preparation batch should be improved, need to study the detecting method of process or quality, expansion in vitro and in vivo evaluation of the relationship between work stripping. |
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| Keywords: | Extended release Nifedipine Tablets Release HPMC |
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