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注射用盐酸川芎嗪与5种常用输液的配伍稳定性考察
引用本文:魏妙华,吴春美,张利平,周慧萍. 注射用盐酸川芎嗪与5种常用输液的配伍稳定性考察[J]. 海峡药学, 2008, 20(3): 26-28
作者姓名:魏妙华  吴春美  张利平  周慧萍
作者单位:浙江省丽水市人民医院,丽水,323000;浙江省丽水市人民医院,丽水,323000;浙江省丽水市人民医院,丽水,323000;浙江省丽水市人民医院,丽水,323000
摘    要:
目的考察注射用盐酸川芎嗪的配伍稳定性。方法模拟临床浓度和使用方法,采用HPLC法测定注射用盐酸川芎嗪与果糖等5种常用输液配伍后的含量变化,同时测定溶液的pH值,观察溶液的颜色及澄明度的变化。结果注射用盐酸川芎嗪与果糖等常用输液配伍后,各项结果在8h内均无明显变化。结论注射用盐酸川芎嗪可与果糖等常用输液配伍使用。

关 键 词:注射用盐酸川芎嗪  输液  配伍  稳定性
文章编号:1006-3765(2008)-03-0026-03

Investigation on compatible stability of Ligustrazini hydrochloridi injection in usual infusions
WEI Miao-hua,WU Chun-mei,ZHANG Li-ping,ZHOU Hui-ping. Investigation on compatible stability of Ligustrazini hydrochloridi injection in usual infusions[J]. Strait Pharmaceutical Journal, 2008, 20(3): 26-28
Authors:WEI Miao-hua  WU Chun-mei  ZHANG Li-ping  ZHOU Hui-ping
Abstract:
OBJECTIVE To study the compatible stability of Ligustrazini hydrochloridi injection.METHODS The pH value of the solution was tested,the solution content was determined by HPLC,the colour and clarity was observed to study the stability of Ligustrazini hydrochloridi injection with common infusions.RESULTS There was no significant changes after matching for eight hours.CONCLUSION Ligustrazini hydrochloridi injection can combine with common infusions.
Keywords:Ligustrazini hydrochloridi injection  Infusion  Compatibility  Stability
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