刺激大脑皮层体感区观察对中缝大核放电的影晌

<正> 近年来,国内外在医学和兽医学临床上,广泛地应用了针刺镇痛.并对针刺镇痛原理也进行了比较广泛地研究,提出针刺镇痛是痛觉传入信息和针刺传入信息在中枢神经系统的不同水平上相互整合作用的

THE EFFECTS OF ELECTRICAL STIMULATION OF CEREBRAL SOMATOSENSORY AREA ON SPONTANEOUS SINGLE DISCHARGE OF NUCLEUS RAPHE MAGNUS

At present, using cortical evoked potentials (CEP) as an index, many researchers have studied the role of the cerebral cortex in acupuncture analgesia. However, to find out whether the cerebral cortex plays a role in acupuncture analgesia, the sudies must first center efforts on relatioship between CEP and pain, and between cerebral cortex and the nucleus raphe magnus (NRM). Thirteen cats weighing 1.8-3kg were used in the present study. All the animals were kept conscious and inmobilized in all the process of the experiment. While somatosenaory area and Xieqi point (邪气穴) were stimulated, the spontaneous single discharge of the nueleus raphe magnus (NRM) were recorded, and at the same time the responses of levels before and after stimulation were observed and compared. The results are as follows: (1) In 55 spontaneous single discharges (SSD), frequency range was 0.5-3/sec, pulse amplitude-250-400μv, and the greatest reached Imv. (2) In 55 spontaneous single discharges, when somatosensory area was stimulated, SSD of all the nucleus raphe magnus were increased. (3) In 12 spontaneous single discharges, SSD were observed under the influences of the acupuncture point and pain stimulation. The results obtained are as follows: 9 SSD were not affected by pain stimulation, whereas, when acupuncture point were stimulated, SSD of the nucleus raphe mugnus were increased.