| 食管癌侵袭转移的分子生物学标志物 |
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| 引用本文： | 范小玲,刘文其. 食管癌侵袭转移的分子生物学标志物[J]. 国际肿瘤学杂志, 2011, 38(10): 774-776. DOI: 10.3760/cma.j.issn.1673-422X.2011.10.018 |
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| 作者姓名： | 范小玲 刘文其 |
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| 作者单位： | 广西医科大学第一附属医院放疗科,南宁,530007 |
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| 摘 要： | 食管癌的侵袭转移与肿瘤发生发展的多个肿瘤标志物有关,其中包括基质金属蛋白酶(MMP)、细胞黏附因子CD44、垂体瘤转化基因等.研究表明,这些肿瘤标志物均在食管癌中过表达,影响食管癌的进展及预后,但其特异性及临床应用价值还有待进一步研究.
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| 关 键 词： | 食管肿瘤 肿瘤转移 肿瘤标记,生物学 |
Biological markers of esophageal carcinoma invasion and metastasis |
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| FAN Xiao-ling,LIU Wen-qi. Biological markers of esophageal carcinoma invasion and metastasis[J]. Journal of International Oncology, 2011, 38(10): 774-776. DOI: 10.3760/cma.j.issn.1673-422X.2011.10.018 |
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| Authors: | FAN Xiao-ling LIU Wen-qi |
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| Affiliation: | Department of Radiation Oncology,First Aiffiated Hospital Guangxi Medical University, Nanning 530007,China |
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| Abstract: | The invasion and metastasis of esophageal carcinoma is associated with several tumor marker on oncogenesi and tumor development,including matrix metalloproteinase,cell adhesion molecules CD44,pituitary-tumour transforming genes.Studies have shown that these tumor markera are over-expression in esophageal carcinoma,which affect the progress and prognosis of esophageal carcinoma,and their specificity and value for clinical application need to be futher studied. |
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| Keywords: | Esophageal neoplasms Neoplasm metastasis Tumor markers,biological |
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