| 硝酸益康栓制备工艺与质量控制 |
| |
| 引用本文： | 张晶,谭晓亮. 硝酸益康栓制备工艺与质量控制[J]. 实用药物与临床, 2005, 8(3): 17-18 |
| |
| 作者姓名： | 张晶 谭晓亮 |
| |
| 作者单位： | 沈阳市中医院,沈阳,110004;沈阳市中医院,沈阳,110004 |
| |
| 摘 要： | 目的研制硝酸益康栓工艺,并制定合适的定量分析方法。方法以半合成脂肪酸甘油脂为基质制备硝酸益康唑栓,以HPLC法测定本品中硝酸益康唑的含量。结果硝酸益康唑的平均回收率为100.1%,RSD为1.13%。结论硝酸益康唑栓工艺可行,HPLC法测定本品中硝酸益康栓的含量可作为控制本品质量的指标。
|
| 关 键 词： | 硝酸益康栓 制备工艺 HPLC 质量标准 |
| 文章编号： | 1673-0070(2005)03-0017-02 |
| 修稿时间： | 2004-08-12 |
Preparation and quality control of econazole nitrate suppositories |
| |
| ZHANG Jing,TAN Xiao-liang. Preparation and quality control of econazole nitrate suppositories[J]. Practical Pharmacy and Clinical Remedies, 2005, 8(3): 17-18 |
| |
| Authors: | ZHANG Jing TAN Xiao-liang |
| |
| Abstract: | Objective To establish the preparation and quality control of econazole nitrate suppositories. Methods Econazole nitrate suppositories were prepared and determined by the HPLC. Results The average of recovery and RSD were 100.1 % and 1.13% respectively. Conclusion The process of econazole nitrate suppositories was built up. Determination of econazole nitrate suppositories by HPLC can be used as method of econazole nitrate suppositories. |
| |
| Keywords: | Econazole nitrate suppositories HPLC Quality control |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
