Nephrotic syndrome and IgA nephropathy in polycystic kidney disease |
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| Authors: | Toru Hiura Hajime Yamazaki Takako Saeki Shotetsu Kawabe Mitsuhiro Ueno Shinichi Nishi Shoji Miyamura Fumitake Gejyo |
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| Affiliation: | (1) Department of Internal Medicine, Nagaoka Red Cross Hospital, 297-1 Terajima-machi, Nagaoka, Niigata 940-2085, Japan;(2) Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medicine, Niigata, Japan |
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| Abstract: | ![]()
A 70-year-old man with polycystic kidney disease developed nephrotic syndrome, deteriorating to renal insufficiency. Histological examination revealed IgA nephropathy. With treatment of prednisolone, an angiotensin-converting enzyme inhibitor, and an angiotensin II receptor-blocker, his proteinuria markedly decreased and renal function was stabilized. This case supports the idea that renal biopsy is needed in patients with polycystic kidney disease with nephrotic-range proteinuria, for appropriate treatment and prevention of renal failure. |
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| Keywords: | Polycystic kidney disease Nephrotic syndrome IgA nephropathy Steroid |
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