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A case of Jarisch–Herxheimer reaction in candidiasis treated with systemic fluconazole
Authors:Marta Muscianese  Francesca Magri  Giulia Pranteda  Guglielmo Pranteda
Abstract:
Jarisch–Herxheimer reaction (JHR) is an acute and self‐limited condition, which commonly occurs after treatment for spirochetal infections. Probably, it corresponds to a transient immunological reaction to endotoxin‐like products released from the microorganism during the therapy. For this reason, JHR may be associated with many other infectious diseases besides syphilis. Here, we report a case of a patient affected by extended cutaneous candidiasis diagnosed by culture examination; a JHR occurred after an accidental overdose of oral fluconazole.
Keywords:candidiasis  fluconazole  Jarisch–  Herxheimer reaction
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