1993年云南省瑞丽等地吸毒者艾滋病病毒感染定群研究

１９９３年３月对已建立一年的吸毒者定群研究现场──云南省德宏州瑞丽市、陇川县及潞西县再次进行调查。本次调查７５５例吸毒者及１０２例配偶。从１９９２年进入定群研究ＨＩＶ阴性的８９例静脉吸毒者中，１９９３年又采到血样有５４例，其中９例血清转阳。瑞丽市、陇川县及潞西县１９９２年和１９９３年静注者血清阳转率（／百观察人年）分别为４３．２％及４０．０％，１２．２％及１２．２％，０％及０％。１９９３年新进入定群研究的１１６例静注者中，采集到血样的有１０４例，发现ＨＩＶ阳性３８例。上述三市县１９９２年及１９９３年入定群研究的静注者的ＨＩＶ感染率分别为８１．８％及８５．７％，４４．６％及４０．０％，５．１％及０％。可以看出血清阳转率的高低与ＨＩＶ感染率高低相吻合。ＨＩＶ阳性者的配偶１９９０、１９９２及１９９３年的ＨＩＶ感染率分别为３．１％、９．８％和７．４％，有上升趋势。潞西县ＨＩＶ阳性者少，静脉注射出现时间晚，但近年来静脉吸毒者比例上升快，值得注意。

Cohort Study of HIV Infection among Drug Users in Ruili and Other Counties in Yunnan Province, China

In 1993,a second survey was conducted in Ruili City and otlier two counties,where a cohort study field was establ ished last year.Seven hundred and fifty five drug users and one hundred and two spouses of HIV infected IDUs were interviwed.Nine samples among 54 from 89 IDUs in cohort were tested as seroconversion.Theseroconversion rate(incidence rate)in IDUs(perhundred person years)in Ruili,Longchuan,and Luxi as well were 40.0,12.2 and 0,res-pectively in 1993,comparing to 43.2,12.2 and 0 in 1992.Thirty eight were tested as positiveamong 108 samples from 116 newly recruited IDOs.The seroprcvalence rates in this three count ieswere 85.7%, 40.0,and 0 in 1993,comparing to81.8%, 44.6% and 5.1% in 1992.A coordination ofthe level between seroconvcrsion and seropreva-lence was observed.A increasing trend of sero-prevalence among the spouses of HIV positiveIDUs was found,the seroprevalence rate were3.1% in 1990,9.8%in 1992 and7.4% in 1993.Moreattent ion should be paid to Luxi where therat io of intravenous drug using increasedrapidly,although fewer positives and laterstarting of drug using was found in this county.