| 新生儿乙肝疫苗第2针接种时间与免疫效果关系研究 |
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| 引用本文： | 陈惠峰,郭志宏,顾云忠,张友金,陈桂尧,杨介者,姜霞玲,沈月根,陶志华,王文刚,姚军,钱本立.新生儿乙肝疫苗第2针接种时间与免疫效果关系研究[J].中华流行病学杂志,1994,15(6):349-350. |
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| 作者姓名： | 陈惠峰 郭志宏 顾云忠 张友金 陈桂尧 杨介者 姜霞玲 沈月根 陶志华 王文刚 姚军 钱本立 |
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| 作者单位： | 浙江省卫生防疫站，嘉兴市郊区卫生防疫站，平湖市卫生防疫站 |
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| 摘 要： | 新生儿乙肝疫苗免疫接种首针“０”和第３针“６”保持不变，将第２针分为３０、４０、５０、６０天组，于第２针免后和全程免后１个月各采血检测，各组抗－ＨＢｓ阳转率和滴度均无组间差异。不论ＨＢｓＡｇ阴性和ＨＢｓＡｇ阳性母亲组的新生儿抗－ＨＢｓ消长变化均与０、１、６程序结果相似。提示对山区、海岛等受客观条件影响大的地区，新生儿乙肝疫苗第２针接种时间可在３０～６０天完成。
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| 关 键 词： | 乙肝痰苗，接种时间 |
A Study on Relation Between Effect of HB Vaccination and Time of the Second Injection |
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| Chen Huifeng,Guo Zhihong,Gu Yunzhong.A Study on Relation Between Effect of HB Vaccination and Time of the Second Injection[J].Chinese Journal of Epidemiology,1994,15(6):349-350. |
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| Authors: | Chen Huifeng Guo Zhihong Gu Yunzhong |
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| Institution: | Chen Huifeng,Guo Zhihong,Gu Yunzhong,et al.Zhejiang ProvincialHygiene and Epidemic Prevention Sta-tion,Hangzhou 310009 |
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| Abstract: | hree kinds of hepatitis B vaccinationschedule in neonates were compared. The sche-dule included 0, 40 day,6 month;50 day, 6 month; 0, 60 day,6 month; and was control- led by the 0, 30 day, 6 month schedule. Theresults showed that there was no statisticallysignificant difference among three kinds ofschedule,no matter who were neonates of HBsAg-positive mother or neonates of HBsAg-ne-gative mother,These indicated that in areaswith poor condition,such as mountain, islsad,the second injection of hepatitis B vaccinein neonates may be completed within 30-60days. |
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| Keywords: | Hepatitis B vaccine Protective rate |
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