Involvement of thyroid gland at non-Hodgkin lymphoma initial diagnosis: 2 pediatric cases] |
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| Authors: | S Frache M O Peter V Laithier A M Bertrand G Thiriez A Menget B Kantelip K Yakouben E Plouvier P S Rohrlich |
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| Affiliation: | 1. Department of Gynecology, Obstetrics and Reproductive Medicine, AP-HM La Conception, Pôle femmes parents enfants, 147 bd Baille, 13005 Marseille, France;2. Institut Méditerranéen de Biodiversité et d''Ecologie marine et continentale (IMBE), Aix Marseille Univ, CNRS, IRD, Univ Avignon, Marseille, France;3. Centre d''Immunophénomique - CIPHE, PHENOMIN, INSERM US012, CNRS UMS3367, UM2 Aix-Marseille Université Marseille, France;4. CNRS, Aix Marseille Univ, IRD, CEREGE UM34, UMR 7330, 13545 Aix en Provence, France;5. Laboratoire de mutagagénèse environnementale, Aix Marseille Univ, Univ Avignon, CNRS, IRD, IMBE, Marseille, France;6. CECOS, Laboratory of Reproductive Biology, Department of Gynecology, Obstetric and Reproductive Medicine, Pôle femmes parents enfants, AP-HM La Conception, 147 bd Baille, 13005 Marseille, France;1. Department of Pathology, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico;2. Department of Pathology, San Cecilio University Hospital. Avenida Madrid 11, Granada, Spain;3. Department of Cardiology and Echocardiogram, Hospital de Especialidades, CMN La Raza, Calle Seris s/n, Col. La Raza, C.P. 02990, Delegación Azcapotzalco, México D.F., Mexico |
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| Abstract: | ![]()
Extranodal thyroid lymphomatous involvement is rare in childhood. We report here 2 children, 1 with vertical transmission-acquired human immunodeficiency virus (HIV), presenting with lymphomatous infiltration of the thyroid gland at diagnosis. One child had infra-clinical endocrine impairment and both responded well to chemotherapy. Although the cases are too scarce to be affirmative, thyroid gland involvement doesn't seem to alter the good prognosis of childhood Burkitt's lymphoma. The third child's cancer in frequency is Non-Hodgkin Lymphomas. Presenting as the initial AIDS event in 1 patient, this case report also highlights the need to systematically propose antiretroviral therapy in vertically HIV infected children. |
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