547株呼吸道感染病原菌的分布及耐药性分析

目的:了解呼吸道感染病原菌的分布及其耐药性。方法:采用常规方法与全自动细菌分析系统鉴定分离的病原菌,用K-B法进行抗菌药物药敏试验。结果:500份呼吸道感染标本中分离出547株病原菌,其中G+球菌196株,占35.83%(196/547)。感染细菌中G-杆菌主要以铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌为主,分别为16.27%,15.36%,13.16%;G+球菌主要以金黄色葡萄球菌和表皮葡萄球菌为主,分别为16.09%,11.15%。G+球菌对青霉素耐药率达100%,G-杆菌对氨苄西林耐药率达93.26%以上。结论:呼吸道感染患者病原菌以G-杆菌为主,对抗生素的耐药呈现上升趋势。

Studies on Distribution & Drug Resistance of 547 Strains Pathogenic Bacteria Isolated from Respiratory Infection Patients

Objective： To investigate the distribution and drug resistance of bacteria isolated from patients with the respiratory tract infection. Methods： The bacteria isolated were identified by traditional methods and bacteria auto-analysis system. The drug sensitivity tests were done with Kirby Bauer method. Results： Five hundred and forty-seven（547） strains were isolated, and 196 swains were Gram-positive（35.83%）, 342 strains were Gram-negative（62.52%）, and 9 sWains were fungus （1.65%）. In isolated Gram-negative bacillus, most are P. Aeruginosa, K.pneumoniae and E. coli, their percentage, are 16.27%, 15.36%, 13.16%, respectively. In isolated Gram-positive coccusbacteria most are S.aureus and S.epidermidis, their percentage respectively are 16.09%, 11.15%.The resistant rate of Gram-positive coccusbacteria to Penicillin was 100%. The resistant rate of Gram-negative bacillus to ampicil was 93.26%. Cunelusion： Most of the bacteria isolated from respiratory infecton patients most are Gram-positive and most of them are antibiotics resistant.