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| 响应面分析法优化牡丹皮中总黄酮的提取工艺 | |
| 引用本文： | 徐金龙,张红梅,徐秀泉. 响应面分析法优化牡丹皮中总黄酮的提取工艺[J]. 中国药房, 2011, 0(27): 2536-2538 |
| 作者姓名： | 徐金龙 张红梅 徐秀泉 |
| 作者单位： | 江苏中兴药业有限公司;江苏大学药学院; |
| 摘 要： | 目的:采用响应面分析法优化牡丹皮中总黄酮的提取工艺。方法:固定提取时间,以乙醇浓度、料液比、提取温度为响应因子,总黄酮得率为响应值,采用3因素3水平的响应面分析法优化牡丹皮中总黄酮的提取工艺参数。结果:各因素对总黄酮提取率的影响大小依次为料液比>提取温度>乙醇浓度;牡丹皮总黄酮的最佳提取工艺条件为乙醇浓度60%,提取温度55℃,料液比1∶40(W/V),在此条件下,牡丹皮总黄酮得率为3.11mg·g-1。结论:试验结果与模型预测值相符,该工艺可用于牡丹皮中总黄酮的提取。 |
| 关 键 词： | 牡丹皮 总黄酮 响应面分析法 提取工艺 |
Optimization of the Extraction Technology of Total Flavonoids from Paeonia suffruticosa by Response Surface Methodology |
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| XU Jin-long,ZHANG Hong-mei XU Xiu-quan. Optimization of the Extraction Technology of Total Flavonoids from Paeonia suffruticosa by Response Surface Methodology[J]. China Pharmacy, 2011, 0(27): 2536-2538 | |
| Authors: | XU Jin-long ZHANG Hong-mei XU Xiu-quan |
| Affiliation: | XU Jin-long,ZHANG Hong-mei(Jiangsu Zhongxing Pharmaceutical Limited Company,Zhenjiang 212009,China) XU Xiu-quan(College of Pharmacy,Jiangsu University,Zhenjiang 212013,China) |
| Abstract: | OBJECTIVE:To optimize the extraction technology of total flavonoids from Paeonia suffruticosa by response surface methodology.METHODS:The extraction time was fixed,the parameters of extraction technology of total flavonoids from P.suffruticosa were optimized by three factors and three levels response methodology using ethanol concentration,ratio of material to liquid and extraction temperature as the response factors and with yeild rate of total flavonoids as response value.RESULTS:The effects of factors in... |
| Keywords: | Paeonia suffruticosa Total flavonoids Response surface methodology Extraction technology |
| 本文献已被 CNKI 维普 等数据库收录！ | |