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| 晚期结直肠癌的化疗进展 | |
| 引用本文： | 李文桦,张 文. 晚期结直肠癌的化疗进展[J]. 中国癌症杂志, 2015, 25(11): 877-889. DOI: 10.3969/j.issn.1007-3969.2015.11.007 |
| 作者姓名： | 李文桦 张 文 |
| 作者单位： | 复旦大学附属肿瘤医院肿瘤内科，复旦大学上海医学院肿瘤学系，上海 200032 |
| 摘 要： | 化疗是晚期结直肠癌的主要治疗手段，以氟尿嘧啶(5-fluorouracil，5-FU)、奥沙利铂和伊立替康为主的三药是晚期肠癌治疗的重要药物，联合化疗和“打打停停”的治疗模式在提高疗效的同时兼顾了治疗的耐受性。新的化疗药物雷替曲塞、替吉奥和TAS-102也在临床中获得应用。就晚期结直肠癌化疗的进展进行综述。 |
| 关 键 词： | 结直肠癌 化疗 转移 |
Advances in chemotherapy for advanced colorectal cancer |
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| LI Wenhua,ZHANG Wen. Advances in chemotherapy for advanced colorectal cancer[J]. China Oncology, 2015, 25(11): 877-889. DOI: 10.3969/j.issn.1007-3969.2015.11.007 | |
| Authors: | LI Wenhua ZHANG Wen |
| Affiliation: | Department of Medical Oncology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China |
| Abstract: | Chemotherapy is the main treatment approach for advanced colorectal cancer. The 5-fluorouracil (5-FU), oxaliplatin and irinotecan are three major chemotherapeutic drugs. The combined chemotherapy and “stop and go” treatment mode increase the efficacy and patients’ tolerance. The new drugs, raltitrexed, S-1 and TAS-102, have been approved for use in cancer treatment. This article reviews the new development in chemotherapy for the treatment of advanced colorectal cancer. |
| Keywords: | Colorectal cancer Chemotherapy Metastases |
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