PCI对冠心病合并2型糖尿病患者HRT的影响

目的 探讨经皮冠状动脉介入(PCI)治疗对不稳定性心绞痛合并2型糖尿病患者窦性心率震荡(HRT)的影响。方法 选择110例不稳定性心绞痛(UAP)合并2型糖尿病患者分为两组:观察组(拟行PCI治疗)57例和对照组(未能进行PCI治疗)53例。两组分别在治疗前及治疗后1月检查动态心电图来计算窦性心率震荡初始值(TO)和窦性心率震荡斜率(TS)。结果 观察组PCI术后1月时TO降低,TS增高(P < 0.05)。治疗1月后,观察组TO明显降低,TS明显增高,与对照组比较差异均有统计学意义(P < 0.05)。观察组患者冠状动脉多支病变组TO增高,TS降低,与单支病变组比较差异均有统计学意义(P < 0.05)。结论 PCI较药物治疗更能有效改善UAP合并2型糖尿病患者的HRT,有条件者应尽早行PCI治疗,从而改善患者的长期预后。

Effects of Percutaneous Coronary Intervention on Sinus Heart Rate Turbulence in Patients with Unstable Angina Pectoris Complicated with Type 2 Diabetes Mellitus

Objective To explore the effects of PCI on sinus heart rate turbulence in patients with unstable angina pectoris (UAP) complicated with type 2 diabetes mellitus. Methods A total of 110 patients with UAP complicated with type 2 diabetes mellitus were selected,then were divided into 57 cases in the observation group and 53 cases in the control group. The two groups were given conventional treatment of UAP and diabetes. Among all the patients,dynamic electrocardiogram was done to calculate turbulence onset (TO) and turbulence slope (TS) before treatment and one month after treatment. Results TO was significantly lower and TS was significantly higher in the observation group at one month after PCI(P < 0.05). Compared with the control group at one month after PCI,TO was significantly lower and TS was significantly higher in the observation group(P < 0.05). TO was significantly lower and TS was significantly higher in multi-vessel group compared with that of single-vessel group(P < 0.05). Conclusion PCI can more effectively improve HRT in patients with UAP complicated with type 2 diabetes mellitus. Patients should undergo PCI therapy to improve the long-term prognosis.