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Polymorphism analysis of the VNTR locus D17S5 in Central Spain |
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| Authors: | E. Arroyo L. Prieto J. M. Ruiz de la Cuesta F. García-Sánchez J. L. Vicario |
| Affiliation: | (1) Servicio de Biología Forense, Departamento de Toxicologia y Legislación Sanitaria, Facultad de Medicina, Universidad Complutense, 28 040 Madrid, Spain;(2) Laboratorio de Histocompatibilidad, Centro de Transfusión, Comunidad Autónoma de Madrid, Menéndez Pelayo, 65, E-28009 Madrid, Spain;(3) Servicio de Biología Forense, Departamento de Toxicologia y Legislación Sanitaria, Facultad de Medicina, Universidad Complutense, E-28 040 Madrid, Spain;(4) Laboratorio de Histocompatibilidad, Centro de Transfusión, Comunidad Auténoma de Madrid, Menéndez Pelayo, 65, E-28009 Madrid, Spain |
| Abstract: | The fragment length polymorphism YNZ22 (D17S5) was analysed for a sample of 207 unrelated individuals living in Madrid (Spanish Caucasians) using PCR-methodology and high resolution separation. Hardy-Weinberg expectations (HWE) were calculated after pooling alleles into four groups. No deviations from HWE were detectable using the conventional  2-test. The power of discrimination was estimated as 0.96 and the mean paternity exclusion chance as 0.7587. A comparison of the allele frequency distribution with those of other Caucasian groups revealed no major differences. |
| Keywords: | Population genetics PCR-FLP D17S5 Spanish population YNZ22 |
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